PAROMOMYCIN SULFATE
1263-89-4 Basic informationMore
- Product Name:PAROMOMYCIN SULFATE
- Synonyms: PAROMOMYCIN SULFATE aminosidinesulfate aminosidinesulphate aminosidinsulfate fi5853 gabbroral D-Streptamine, O-2,6-diamino-2,6-dideoxy-b-L-idopyranosyl-(13)-O-b-D-ribofuranosyl-(15)-O-[2-amino-2-deoxy-a-D-glucopyranosyl-(14)]-2-deoxy-, sulfate (salt) (8CI) D-Streptamine, O-2-amino-2-deoxy-a-D-glucopyranosyl-(14)-O-[O-2,6-diamino-2,6-dideoxy-b-L-idopyranosyl-(13)-b-D-ribofuranosyl-(15)]-2-deoxy-, sulfate (salt) (9CI)
- CAS:1263-89-4
- MF:C23H47N5O18S
- MW:713.71
- EINECS:215-031-7
- Mol File:1263-89-4.mol
USE
<p>PAROMOMYCIN SULFATE is White to Off-White Solid</p>
<p>PAROMOMYCIN SULFATE is an aminogycoside antibiotic designed to fight intestinal infections such as cryptosporidiosis, amoebiasis, and leishmaniasis. Its antiprotozoal activity makes it an effecive histomonostatic feed addit ive in turkey poults experimentally infected with Histomonas meleagridis.</p>
The isolation of paromomycin (Humatin) was reported in1956 from a fermentation with a Streptomyces sp. (PD04998), a strain said to resemble S. rimosus very closely.The parent organism had been obtained from soil samplescollected in Colombia. Paromomycin, however, moreclosely resembles neomycin and streptomycin in antibioticactivity than it does oxytetracycline, the antibiotic obtainedfrom S. rimosus.<br>Paromomycin has broad-spectrum antibacterial activityand has been used for the treatment of GI infections causedby Salmonella and Shigella spp., and enteropathogenic E.coli. Currently, however, its use is restricted largely to thetreatment of intestinal amebiasis. Paromomycin is soluble inwater and stable to heat over a wide pH range.Purify it by dissolving it in H2O (0.5g/10mL) and adding excess EtOH, filter or collect and wash with EtOH, then Et2O by centrifugation, and dry it in vacuo. An aqueous solution is stable at 37o for a week but longer at 0-5o. The free base [7542-37-2] is a white amorphous powder which should be stored under N2 because it is strongly basic and can absorb CO2 from the atmosphere. It is soluble in MeOH (less soluble in EtOH) and has [] D 25 +65o (c 1.5, MeOH). It is an antimicrobial against Gram +ve and Gram –ve bacteria and is antiamoebic. It inhibits initiation and peptide elongation during protein synthesis. [Haskell et al. J Am Chem Soc 8 1 , 3480, 3482 1959, Hichens & Rinehart J Am Chem Soc 85 1547 1963, Beilstein 18 III/IV 7534.]
Lastest Price from PAROMOMYCIN SULFATE manufacturers
- PAROMOMYCIN SULFATE
- US $610.00 /KG
- CAS:1263-89-4
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1-10mt
- 2025-01-02
- Paromomycin Sulfate
- US $0.00 /g
- CAS:1263-89-4
- Min. Order: 1g
- Purity: More Than 99%
- Supply Ability: 50kg/Month
- 2024-12-30
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- Company Name:Hubei Weideli Chemical Reagent Co.,Ltd.
- Tel: 13339985473
- Products Intro:Product Name:Paromomycin sulfate
CAS:1263-89-4
Purity:99% HPLC Package:1KG;5KG;10KG - CB Index:58
- Related Information:Catalog(4918)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:ParoMoMycin sulphate
CAS:1263-89-4
Package:1g,25g,5g More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:ParoMoMycin sulfate salt
CAS:1263-89-4
Purity:98% HPLC Package:1g;5g;25g;100g More... - CB Index:69
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- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386
- Products Intro:Product Name:Paromomycin Sulfate
CAS:1263-89-4
Purity:94.0% LC Package:1G,5G More... - CB Index:81
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- Company Name:Beijing HwrkChemical Technology Co., Ltd
- Tel:010-89508211 18501085097
- Products Intro:Product Name:Paromomycin sulfate
CAS:1263-89-4
Purity:98.00% Package:5g - CB Index:55
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- Company Name:Energy Chemical
- Tel:021-021-58432009 400-005-6266
- Products Intro:Product Name:PAROMOMYCIN SULFATE
CAS:1263-89-4
Purity:98% Package:1g;5g;25g;100g;100mg;10g;250g;50g Remarks:NULL More... - CB Index:61
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- Company Name:Adamas Reagent, Ltd.
- Tel:400-6009262 16621234537
- Products Intro:Product Name:Paromomycin Sulfate
CAS:1263-89-4
Purity:98% Package:1g;5g;25g;100g;500g - CB Index:59
- Related Information:Catalog(14103)