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Malononitrile

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The in vitro metabolsim of malononitrile has been described by Stern et al. In the presence of thiosulphate, brain, liver and kidney slices metabolized malononitrile to thiocyanate. The formation of thiocyanate from malononitrile and thiosulphate was greatest in the presence of liver slices, lowest in brain, and intermediate with kidney slices. The liver enzyme system was saturated at a concentration of 3.3 mM malononitrile and a pH optimum of 7.0. This enzyme system was inhibited by cysteine and glutathione and inactivated by boiling. Stern et al indicated that thiosulphate increased cyanide and thiocyanate formed from malononitrile in tissue slices.
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  • Malononitrile
  • US $30.00 /kg
  • CAS:109-77-3
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 1000tons
  • 2023-09-07
  • Malononitrile
  • US $9.00 /KG
  • CAS:109-77-3
  • Min. Order: 1KG
  • Purity: 99.9
  • Supply Ability: 1 ton
  • 2023-05-12

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