Eribulin

• Product Name:Eribulin
• Synonyms: Eribulin B 1939 E 7389 ER 086526 US-DMF No. : 035118 DMF No. : 035118 Eribulin USP/EP/BP (1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-Amino-2- hydroxypropyl]-21-methoxy-14-methyl-8,15-bis(methylene)-2,19,30,34,37,39,40,41-octaoxanonacyclo [24.9.2.1 3,32 .1 3,33 .1 6,9 .1 12,16 .0 18,22 .0 29,36 .0 31,35 ]hentetracontan-24-one
• CAS:253128-41-5
• MF:C40H59NO11
• MW:729.9
• EINECS:803-583-7
• Mol File:253128-41-5.mol
• 

The U.S. FDA approved eribulin mesylate (also referred to as E7389) in November 2010 for the treatment of metastatic breast cancer (MBC) for patients who previously received at least two chemotherapeutic regimens for late-stage disease. Eribulin is a synthetic analog of the marine natural product halichondrin B, which is isolated from the sea sponge Halichondria okadai. Eribulin retains most of the structural elements that constitute the right hand side of halichondrin B; structure–activity relationship (SAR) studies suggested that the antitumor activity of halichondrin B resides in that part of the molecule . Eribulin is a microtubule inhibitor that binds close to the vinca-binding site of tubulin. Unlike most tubulin inhibitors like taxanes, epothilones, and vinca alkaloids that inhibit microtubule dynamic instability by changing tubulin addition and loss parameters, eribulin’s effects on dynamic instability are novel in that eribulin inhibits the growth phase of microtubules without affecting the shortening phase by binding to microtubule plus ends.

• Eribulin
• 
• US $1.00 /g
• CAS:441015-17-6
• Min. Order: 1g
• Purity: 85.0-99.8%
• Supply Ability: 20tons
• 2024-10-22

• Eribulin
• 
• US $12.00 /g
• CAS:253128-41-5
• Min. Order: 1KG
• Purity: 99%
• Supply Ability: 5ton/Month
• 2021-11-27

• Company Name:WuYan Pharmaceutical Technology (Shanghai) Co., Ltd.
• Tel:021-61001086 13671938079
• Products Intro:Product Name:Eribulin
  CAS:253128-41-5
  Purity:99%，单杂0.1%以下 Package:1g;10g;100g More...
• CB Index:55
• Related Information:Catalog(105)

• Company Name:Hubei widely chemical technology Co., Ltd.
• Tel:027-83989310 18627915365
• Products Intro:Product Name:Brinzolamide
  CAS:253128-41-5
  Purity:99% Package:10mg/RMB 9000;100mg1000mg
• CB Index:58
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• Company Name:Abydos Scientific
• Tel:025-84767922 18936879710
• Products Intro:Product Name:Eribulin
  CAS:253128-41-5
  Purity:0.99 Package:25kg;10kg;5kg;1kg More...
• CB Index:58
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• Company Name:Nanjing Becas pharmatech Ltd.
• Tel: 13912903754
• Products Intro:Product Name:Eribulin
  CAS:253128-41-5
  Purity:0.99 Package:1g;5g
• CB Index:58
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• Company Name:DebyeTec.com Inc.
• Tel:18086626237 18086626237
• Products Intro:Product Name:Trabectedin
  CAS:253128-41-5
  Purity:98+ Package:250mg
• CB Index:56
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• Company Name:C N C H E M U N I O N C O . , L T D .
• Tel:17653471880 17653471880
• Products Intro:Product Name:Eribulin
  CAS:253128-41-5
  Purity:99% Package:1g/RMB 80000;10g25g
• CB Index:58
• Related Information:Catalog(104)

• Company Name:Chemvon Biotechnology Co., Ltd
• Tel:021-50790412
• Products Intro:Product Name:Eribulin
  CAS:253128-41-5
  Purity:99% HPLC Package:1g;50g;100g;1kg More...
• CB Index:57
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• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:Eribulin (B1939
  CAS:253128-41-5
  Purity:98%+ HPLC Package:50mg;100mg;500mg;1g Remarks:Biochemical Reagents; Pharmaceutical Intermediates More...
• CB Index:61
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