Mk-2461 .
917879-39-1 Basic informationMore
- Product Name:Mk-2461 .
- Synonyms: Mk-2461 . N-[(2R)-1,4-dioxan-2-ylMethyl]-N-Methyl{[5-(1-Methyl-1H-pyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-14-yl]aMino}sulfonaMide N-((2R)-1,4-Dioxan-2-ylmethyl)-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfamide Mk-2461 . N-[(2R)-1,4-dioxan-2-ylMethyl]-N-Methyl{[5-(1-Methyl-1H-pyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-14-yl]aMino}sulfonaMide 9-[[[(2R)-1,4-DIOXAN-2-YL]METHYL-METHYLSULFAMOYL]AMINO]-2-(1-METHYLPYRAZOL-4-YL)-11-OXOBENZO[1,2]CYCLOHEPTA[2,4-B]PYRIDINE MK-2461;MK2461;MK 2461 CS-528 Sulfamide, N-[(2R)-1,4-dioxan-2-ylmethyl]-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-
- CAS:917879-39-1
- MF:C24H25N5O5S
- MW:495.55
- EINECS:
- Mol File:917879-39-1.mol
-
USE
MK-2461 is a novel ATP-competitive multitargeted kinase inhibitor that preferentially inhibits the activated c-Met receptor. MK-2461 is also a potent inhibitor of Ron, Flt1, Flt 3, PDGFRβ, and Mer receptors. Recent studies show that MK-2461 siginifciantly suppresses tumor growth of GTL-16 xenografts in mice and MK-2461 treatments effectively inhibit the growth of NIH3T3 tumors harboring c-Met single nucleotide mutants T3936C and T3997C.
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:MK-2461
CAS:917879-39-1
Package:100Mg,250Mg More... - CB Index:76
- Related Information:Catalog(94657)
- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
- Products Intro:Product Name:Mk-2461 .
CAS:917879-39-1
Purity:>98% Package:10MG Remarks:2390 More... - CB Index:58
- Related Information:Catalog(4727)
- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel:400-400-6206333 18521732826
- Products Intro:Product Name:MK-2461
CAS:917879-39-1
Purity:10mM in DMSO Package:1ml/RMB 1762.90 More... - CB Index:65
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