PROTEIN C

• Product Name:PROTEIN C
• Synonyms: PROTEIN C, ACTIVATED, HUMAN PROTEIN C PROTEIN C, ACTIVATED PROTEIN C, HUMAN PLASMA PROTEIN C CONTROL PLASMA PROTEIN C, HUMAN PROTEIN C, ACTIVATED, HUMAN PLASMA HUMAN PROTEIN C
• CAS:42617-41-4
• MF:
• MW:0
• EINECS:
• Mol File:Mol File
• 

Drotrecogin alfa was introduced in the US as a new intravenous treatment for the reduction of mortality in adult patients with severe sepsis associated with acute organ dysfunction. Drotrecogin aifa is the first recombinant activated protein C expressed in human kidney 293 cells. Activated protein C₁ an endogenous serine protease, acts as an antithrombotic via inhibition of factor Va and Vllla, promotes fibrinolysis via inactivation of plasminogen-activator inhibitor-1 and exerts an anti-inflammatory effect by inhibiting the production of inflammatory cytokines (tumor necrosis factor-alpha, interieukin-1 and 6) by monocytes. It was shown that the majority of patients with sepsis have reduced levels of activated protein C. In a baboon model of lethal E. coli sepsis, administration of activated protein C reduced mortality. In a phase III clinical trial, intravenous infusion of drotrecogin alfa at a dose of 24 μg/kg/h over 96 h significantly reduced the risk of death compared with placebo in patients with severe sepsis. However, an increased risk of serious bleeding has been associated with the administration of the drug.

• Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
• Tel:821-50328103-801 18930552037
• Products Intro:Product Name:PROTEIN C
  CAS:42617-41-4
  Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
• CB Index:69
• Related Information:Catalog(15839)

• Company Name:Sigma-Aldrich
• Tel:021-61415566 800-8193336
• Products Intro:Product Name:ProteinC
  CAS:42617-41-4
  Purity:>=90% (SDS-PAGE) Package:0.1mg Remarks:P2200 More...
• CB Index:80
• Related Information:Catalog(51456)

• Company Name:Shanghai Huzhen Industrial Co., LTD
• Tel:021-60345367 13916550749
• Products Intro:Product Name:protein C
  CAS:42617-41-4
  Purity:> 99% Package:50ul/RMB 1138;100ul/RMB 1880;200ul/RMB 2900 Remarks:Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; EC 3.4.21.69; PC; PROC; PROC1; Vitamin K dependent protein C precursor; APC; EC 3.4.21.69; PC; proC; PRO
• CB Index:58
• Related Information:Catalog(9966)

• Company Name:-gzshuangjian
• Tel:13922214953
• Products Intro:Product Name:DP-25
  Purity:19-21 Package:kg
• CB Index:58
• Related Information:Catalog(35)

• Company Name:Shanghai Tongwei Biotechnology Co., Ltd
• Tel:021-66980655
• Products Intro:Product Name:activated protein C
  CAS:42617-41-4
  
• CB Index:58
• Related Information:Catalog(6377)