Amifostine
20537-88-6 Basic informationMore
- Product Name:Amifostine
- Synonyms: γphos Fosteamine 2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721 Ethiotas S-2-[(3-Aminopropyl)amino]ethanethiol dihydrogen phosphate ester Amifostine,2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721 AMifostine anhydrous AMifostine(Ethiofos)
- CAS:20537-88-6
- MF:C5H15N2O3PS
- MW:214.22
- EINECS:633-786-4
- Mol File:20537-88-6.mol
-
USE
Amifostine, an organic thiophosphate, was introduced for the reduction
of cisplatin-induced renal toxicity in patients with advanced ovarian cancer. It is also a
radio-protective agent. Amifostine is a prodrug which is rapidly dephosphorylated,
preferentially in non-tumor tissues to the active thiol. This agent binds to
chemotherapeutic drugs and free radicals released by radiotherapy. The protective
effect of amifostine was observed in a wide range of normal organs including bone
marrow and gastrointestinal mucosa without interfering with the anti-tumor effect of
chemohadiotherapy, indicating an increased therapeutic index for existing cancer
treatment. Amifostine is also being evaluated as a cytoprotective in other types of
tumors including lung, breast, head and neck cancers. It was reported to be a potent
mucolytic with potential in cystic fibrosis.
Lastest Price from Amifostine manufacturers
- Amifostine
-
- US $0.00 /g
- CAS:20537-88-6
- Min. Order: 1g
- Purity: 98.0%
- Supply Ability: 5kg/month
- 2023-11-15
- Amifostine
-
- US $10.00 /Kg/Bag
- CAS:20537-88-6
- Min. Order: 1Kg/Bag
- Purity: 99%
- Supply Ability: 20 Tons
- 2022-06-02
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- Company Name:MedBioPharmaceutical Technology Inc
- Tel:021-69568360 18916172912
- Products Intro:Product Name:Amifostine
CAS:20537-88-6
Purity:98% Package:10mg; 50mg Remarks:Medbio - CB Index:58
- Related Information:Catalog(8141)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:AMifostine
CAS:20537-88-6
Package:100Mg,10Mg More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:Nanjing Chemlin Chemical Co., Ltd
- Tel:025-83697070
- Products Intro:Product Name:Amifostine
CAS:20537-88-6
Purity:98% Package:5KG;1KG More... - CB Index:64
- Related Information:Catalog(17940)
- Company Name:XiaoGan ShenYuan ChemPharm co,ltd
- Tel:0712-0712-2580635 15527768850
- Products Intro:CAS:20537-88-6
More... - CB Index:52
- Related Information:Catalog(8849)
- Company Name:China Langchem Inc.
- Tel:021-58956006 15800617331
- Products Intro:Product Name:Amifostine
CAS:20537-88-6
Purity:98% Package:1kg;5kg;100kg Remarks:1g/650 More... - CB Index:57
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