UK-371804
256477-09-5 Basic informationMore
- Product Name:UK-371804
- Synonyms: UK-371804 Urokinase inhibitor 1 Urokinase inhitibor 1 UK-371804 (Urokinase inhitibor 1) Alanine, N-[[1-[(aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methyl- N-[[1-[(Aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methylalanine UK 371804,UK-371804,Inhibitor,PAI-1,inhibit,Plasminogen activator inhibitor-1
- CAS:256477-09-5
- MF:C14H16ClN5O4S
- MW:385.83
- EINECS:
- Mol File:256477-09-5.mol
-
USE
UK-371804 is a potent and selectiveurokinase-type plasmogen activator (uPA)inhibitor. It has excellent selectivityover tPA, plasmin, Factor IXa and Xa.In vitro, it is able to inhibit exogenous uPA in human chronic wound fluid (IC50=0.89 microM). In vivo, in a porcine acute excisional wound modelfollowing topical delivery, it is able to penetrate into pig wounds and inhibit exogenous uPA activity with no adverse effect on wound healing parameters. It has the potential for the treatment of chronic dermal ulcers.
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- Company Name:Shanghai Lollane Biological Technology Co.,Ltd.
- Tel:021-52996696，15000506266 15000506266
- Products Intro:Product Name:UK-371804 (Urokinase inhitibor 1）
CAS:256477-09-5
Purity:98% HPLC Package:5mg，10mg，50mg，100mg，1g，5g - CB Index:55
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- Company Name:Shanghaizehan biopharma technology co., Ltd.
- Tel:021-61350663 13052117465
- Products Intro:Product Name:UK-371804
CAS:256477-09-5
Purity:98% Package:1g/;5g/ - CB Index:55
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- Company Name:Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel: 15076683720
- Products Intro:Product Name:UK-371804HCl
CAS:256477-09-5
Purity:>98% Package:2g Remarks:2g More... - CB Index:55
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- Company Name:ShangHai Biochempartner Co.,Ltd
- Tel:17754423994 17754423994
- Products Intro:Product Name:UK-371804
CAS:256477-09-5
Purity:98% HPLC LCMS Package:100mg;1g More... - CB Index:62
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- Company Name:Shanghai Rechem science Co., Ltd.
- Tel:21-31433387 15618786686
- Products Intro:CAS:256477-09-5
Purity:98% Package:1g/;10g/ - CB Index:58
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- Company Name:Shanghai Chaolan Chemical Technology Center
- Tel:QQ:65489617 15618227136
- Products Intro:Product Name:UK-371804 (Urokinase inhitibor 1）
CAS:256477-09-5
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G More... - CB Index:58
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- Company Name:Shanghai SuperLan Chemcial Technique Centre
- Tel:021-2022843681 15618226720
- Products Intro:Product Name:UK-371804 (Urokinase inhitibor 1）
CAS:256477-09-5
Purity:95% Package:1G,5G,10G,50G,100G,1KG More... - CB Index:58
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- Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
- Tel:010-60605840 18892239720
- Products Intro:Product Name:UK-371804 HCl
CAS:256477-09-5
Purity:98% (HPLC) Package:5mg;100mg;25mg More... - CB Index:58
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