PHENCYCLIDINE
77-10-1 Basic informationMore
- Product Name:PHENCYCLIDINE
- Synonyms: Methanol(test Phencyclidine(PCP),1.0mg/mL) PCP (Phencyclidine) solution 1-(1-PHENYLCYCLOHEXYL)PIPERIDINE Pcp (phencyclidine) Phencyclidine (pcp) Phencylidine Piperidine, 1-(1-phenylcyclohexyl)- 1-(1-Phenylcyclohexyl)piperidine solution, PCP solution
- CAS:77-10-1
- MF:C17H25N
- MW:243.39
- EINECS:
- Mol File:77-10-1.mol
USE
Phencyclidine was introduced as a dissociative anestheticfor animals. Its close structural relative ketamine is still soused and may be used in humans. In humans,PCP produces a sense of intoxication, hallucinogenic experiencesnot unlike those produced by the anticholinergic hallucinogens,and often, amnesia.<br/>The drug affects many systems, including those of NE,DA, and 5-HT. It has been proposed that PCP (and certainother psychotomimetics) produces a unique pattern of activationof ventral tegumental area dopaminergic neurons.Itblocks glutaminergic N-methyl-D-aspartate receptors.Thisaction is the basis for many of its CNS effects. PCP itself appearsto be the active agent. The psychotic state produced bythis drug is also cited as a better model than amphetaminepsychosis for the psychotic state of schizophrenia.
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