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17-AAG

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Geldanamycin is a potent inhibitor of Hsp90 that exhibits severe hepatotoxicity when used in vivo. 17-AAG is an analog of geldanamycin which has potent in vivo activity and reduced toxicity. Like other Hsp90 inhibitors, 17-AAG has diverse anti-tumor actions and has potential in treating certain types of cancer. 17-AAG inhibits the growth of prostate cancer cell lines (IC50 = 25-45 nM). 17-AAG promotes the degradation of HER2 and induces growth arrest and apoptosis in breast cancer cells overexpressing HER2 (IC50 = 4-72 nM).
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  • Company Name:Shanghai Chaolan Chemical Technology Center
  • Tel:QQ:65489617 15618227136
  • Products Intro:Product Name:17-AAG
    CAS:75747-14-7
    Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
  • CB Index:58
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  • Company Name:Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
  • Tel:18049165724 13186333400
  • Products Intro:Product Name:Tiratinib
    CAS:75747-14-7
    Purity:98% HPLC Package:mg g kg t
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  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:010-82848833 400-666-7788
  • Products Intro:Product Name:17-(Allylamino)-17-demethoxygeldanamycin
    CAS:75747-14-7
    Package:10MG More...
  • CB Index:76
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  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:821-50328103-801 18930552037
  • Products Intro:Product Name:17-AAG;17-DeMethoxy-17-(2-propenylaMino)geldanaMycin
    CAS:75747-14-7
    Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
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  • Company Name:Chembest Research Laboratories Limited
  • Tel:021-20908456
  • Products Intro:Product Name:Telatinib(TanespiMycin,KOS-953, 17-AAG,NSC 330507)
    CAS:75747-14-7
    Remarks:C14228 More...
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