17-AAG
75747-14-7 Basic informationMore
- Product Name:17-AAG
- Synonyms: GELDANAMYCIN,17-DEMETHOXY-17-(2-PROPENYLAMINO)- CP 127374 ALLYLAMINOGELDANAMYCIN NSC-330507 17-(ALLYLAMINO)-17-DEMETHOXYGELDANAMYCIN 17-(ALLYLAMINO)-17-DESMETHOXYGELDANAMYCIN 17-(ALLYLAMINO)-17-DIMETHOXYGELDANAMYCIN 17-ALLYLAMINOGELDANAMYCIN
- CAS:75747-14-7
- MF:C31H43N3O8
- MW:585.69
- EINECS:
- Mol File:75747-14-7.mol
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USE
Geldanamycin is a potent inhibitor of Hsp90 that exhibits severe hepatotoxicity when used in vivo. 17-AAG is an analog of geldanamycin which has potent in vivo activity and reduced toxicity. Like other Hsp90 inhibitors, 17-AAG has diverse anti-tumor actions and has potential in treating certain types of cancer. 17-AAG inhibits the growth of prostate cancer cell lines (IC50 = 25-45 nM). 17-AAG promotes the degradation of HER2 and induces growth arrest and apoptosis in breast cancer cells overexpressing HER2 (IC50 = 4-72 nM).
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- Company Name:Shanghai Chaolan Chemical Technology Center
- Tel:QQ:65489617 15618227136
- Products Intro:Product Name:17-AAG
CAS:75747-14-7
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G - CB Index:58
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- Company Name:Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
- Tel:18049165724 13186333400
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CAS:75747-14-7
Purity:98% HPLC Package:mg g kg t - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:17-(Allylamino)-17-demethoxygeldanamycin
CAS:75747-14-7
Package:10MG More... - CB Index:76
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:17-AAG;17-DeMethoxy-17-(2-propenylaMino)geldanaMycin
CAS:75747-14-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:Chembest Research Laboratories Limited
- Tel:021-20908456
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CAS:75747-14-7
Remarks:C14228 More... - CB Index:61
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