Nalidixic acid
389-08-2 Basic informationMore
- Product Name:Nalidixic acid
- Synonyms: uroman uroneg uropan Win18,320 Wintomylon Nalidixic acid, Antibiotic for Culture Media Use Only Nalidixic acid, 1,4-Dihydro-1-ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8
- CAS:389-08-2
- MF:C12H12N2O3
- MW:232.24
- EINECS:206-864-7
- Mol File:389-08-2.mol
-
USE
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (NegGram) occurs as a pale buff crystalline powder that is sparingly soluble in water and ether but solublein most polar organic solvents.Nalidixic acid is useful in the treatment of urinary tractinfections in which Gram-negative bacteria predominate.The activity against indole-positive Proteus spp. is particularlynoteworthy, and nalidixic acid and its congeners representimportant alternatives for the treatment of urinary tractinfections caused by strains of these bacteria resistant toother agents. Nalidixic acid is rapidly absorbed, extensivelymetabolized, and rapidly excreted after oral administration.The 7-hydroxymethyl metabolite is significantly more activethan the parent compound. Further metabolism of theactive metabolite to inactive glucuronide and 7-carboxylicacid metabolites also occurs. Nalidixic acid possesses at1/2elim of 6 to 7 hours. It is eliminated, in part, unchanged inthe urine and 80% as metabolites.
Lastest Price from Nalidixic acid manufacturers
- Nalidixic acid
-
- US $0.00 /kg
- CAS:389-08-2
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 20 tons
- 2024-10-25
- Nalidixic acid
-
- US $1.00 /KG
- CAS:389-08-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20t
- 2024-06-26
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Nalidixic acid, 99%
CAS:389-08-2
Purity:99% Package:100G;25G;5G More... - CB Index:76
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- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
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- Products Intro:Product Name:Nalidixic Acid
CAS:389-08-2
Purity:>95.0%(T) Package:25g;500g Remarks:N0490 More... - CB Index:62
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
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- Products Intro:Product Name:Nalidixic acid
CAS:389-08-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:TCI (Shanghai) Development Co., Ltd.
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CAS:389-08-2
Purity:95.0% T Package:25G More... - CB Index:81
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- Company Name:Energy Chemical
- Tel:021-021-58432009 400-005-6266
- Products Intro:Product Name:Nalidixic acid
CAS:389-08-2
Purity:99% Package:100g,25g,5g More... - CB Index:61
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- Products Intro:Product Name:Nalidixic Acid
CAS:389-08-2
Purity:BR+98% Package:1g;5g;25g;100g;500g Remarks:53818 - CB Index:59
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