Docetaxel
114977-28-5 Basic informationMore
- Product Name:Docetaxel
- Synonyms: Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)- Docetaxel N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyl taxol Taxotere anhydrous n-debenzoyl-n-tert-butoxycarbonyl-10-deacetyl taxol )benz(1,2-b)oxet-9-ylester,(2ar-(2a-alpha,4-beta,4a-beta,6-beta,9-alpha(alph Benzenepropanoic acid, b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trih ydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (aR,bS)- DOCETAXEL ANHYDROUS 99.5% Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-
- CAS:114977-28-5
- MF:C43H53NO14
- MW:807.88
- EINECS:601-339-2
- Mol File:114977-28-5.mol
USE
Docetaxel, a semi-synthetic product from the taxoid family, was launched in
1995 first in South Africa and subsequently in several other markets for the treatment of
ovarian, breast and non-small cell lung cancers. Like the naturally occurring antitumor
agent paclitaxel, the first marketed taxoid, docetaxel promotes both the rate and extent
of tubulin assembly into stable microtubules and inhibits their depolymerization. It acts
as a mitotic spindle poison and induces a mitotic block in proliferating cells. This
mechanism of action for taxoids is unique from other classes of anticancer agents.
Docetaxel was reported to be twice as potent as paclitaxel in several in vitro protocols
and also exhibit higher cytotoxicity. Clinical trials are on going for docetaxel for other
types of tumors including pancreatic, gastric, head and neck cancers and soft tissue
sarcomas.
Lastest Price from Docetaxel manufacturers
- Docetaxel
- US $43.00-35.00/Grams
- CAS:114977-28-5
- Min. Order: 1Grams
- Purity: 99.99%
- Supply Ability: 100Tons
- 2024-04-19
- Docetaxel
- US $0.00 /kg
- CAS:114977-28-5
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20tons
- 2024-04-15
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- Company Name:Wuhan Ying Yuan Bei Biological Limited
- Tel:13349903920; 13349903920
- Products Intro:Product Name:Docetaxel
CAS:114977-28-5
Purity:0.99 Package:kg Remarks:1kg - CB Index:58
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- Company Name:Nanjing Digger Medical Technology Co. Ltd.
- Tel:025-025-51191215 18013836722
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CAS:114977-28-5
Purity:99% HPLC USP38 Package:1g/;5g/;10g/;25g/;50g/;100g/;500g/ More... - CB Index:58
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- Company Name:Tongchuang Pharma(Suzhou). Co., Ltd.
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- Company Name:Wuhan Qiaofeng Chemical Technology Co., Ltd.
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Purity:98% - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
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CAS:114977-28-5
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- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
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CAS:114977-28-5
Purity:>98.0%(LC) Package:100Mg Remarks:D4102 More... - CB Index:62
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
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- Products Intro:Product Name:Docetaxel;[2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-[[(1,1-DiMethylethoxy)carbonyl]aMino]-α-hydroxy-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyc
CAS:114977-28-5
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15848)