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9-keto Fluprostenol isopropyl ester

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<p>Fluprostenol is a well-studied, potent analog of prostaglandin F2α (PGF2α) and acts primarily through the FP receptor.&nbsp; 9-keto Fluprostenol is an analog of PGE2 with structural modifications intended to give it a prolonged half-life and greater potency. 9-keto Fluprostenol isopropyl ester has the potential to act as an EP agonist in prodrug form. However, no studies on the pharmacology of this compound have been published to date. In addition 9-keto fluprostenol isopropyl ester is a potential metabolite of Travoprost, which is the Alcon trade name for fluprostenol isopropyl ester. In monkey cornea, this transformation was observed as a product of NADP+-dependent 15-hydroxyprostaglandin dehydrogenase when the closely related analog Latanoprost was used as a substrate. Certain F-series prostaglandins have been shown to be converted to the corresponding E-series compounds in rabbit liver and human platelet preparations.</p>

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  • Company Name:ChemStrong Scientific Co.,Ltd
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  • Products Intro:Product Name:Travoprost Impurity 21
    CAS:1219032-18-4
    Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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  • Company Name:Shanghai EFE Biological Technology Co., Ltd.
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  • Products Intro:Product Name:9-keto Fluprostenol isopropyl ester
    CAS:1219032-18-4
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  • Products Intro:Product Name:Travoprost Impurity 16(9-keto Fluprostenol Isopropyl Ester)
    CAS:1219032-18-4
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  • Products Intro:Product Name:Travoprost 12
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    Purity:98%以上 Package:10mg;50mg;100mg等多种规格 Remarks:REF-T61013
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  • Products Intro:Product Name:Travoprost
    CAS:1219032-18-4
    Purity:98% HPLC Package:25mg,50mg,100mg
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