Azoles
421581-70-6 Basic informationMore
- Product Name:Azoles
- Synonyms: Azoles 2-(3-Bromophenyl)-5-(trichloromethyl)-1,3,4-oxadiazole 2-(3-Bromophenyl)-5-trichloromethyl-1,3,4-oxadiazole 1-(7-Bromobenzofuran-2-yl)ethanone 2-Acetyl-7-methylbenzofuran 3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole 3-(4-Bromophenyl)-5-cyclohexyl-1,2,4-oxadiazole 5-(2-Chlorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole
- CAS:421581-70-6
- MF:C14H8FN3O3
- MW:285.23
- EINECS:
- Mol File:421581-70-6.mol
-
USE
A large group of synthetic agents, which includes drugs used in
bacterial and parasitic infections (5-nitroimidazoles;
benzimidazoles). Antifungal azoles have in common
an imidazole or triazole ring with N-carbon substitution. The
activity is essentially fungistatic, but some of the newer triazoles
exert fungicidal effects at therapeutic concentrations.
They are effective in the topical treatment of dermatophytoses
and superficial forms of candidosis; several are suitable
for systemic administration.<br/>
Several molecular mechanisms of resistance have been elucidated.
These include overexpression of efflux pump genes,
point mutations in the gene that encodes the target enzyme,
lanosterol demethylase, and overexpression of this gene.
Changes in other enzymes involved in ergosterol biosynthesis,
such as sterol desaturase, may also contribute to azole
resistance.
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- Company Name:Energy Chemical
- Tel:021-021-58432009 400-005-6266
- Products Intro:Product Name:5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole
CAS:421581-70-6
Purity:97% Package:1g,5g More... - CB Index:61
- Related Information:Catalog(44700)
- Company Name:Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
- Tel:025-66099280 17798518460
- Products Intro:Product Name:5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole
CAS:421581-70-6
Purity:95% Package:1g;5g;10g More... - CB Index:55
- Related Information:Catalog(19918)
- Company Name:Amadis Chemical Company Limited
- Tel:571-89925085
- Products Intro:Product Name:5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole
CAS:421581-70-6
Purity:0.97 Package:mgs,gs,kgs Remarks:A872938 - CB Index:58
- Related Information:Catalog(131980)
- Company Name:Career Henan Chemica Co
- Tel:+86-0371-86658258 15093356674;
- Products Intro:Product Name:Azoles
CAS:421581-70-6
Purity:99% Jessie@coreychem.com Package:1g;2.3USD - CB Index:58
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