Alitame
80863-62-3 Basic informationMore
- Product Name:Alitame
- Synonyms: (S)-3-amino-4-(((R)-1-amino-1-oxopropan-2-yl)(2,2,4,4-tetramethylthietan-3-yl)amino)-4-oxobutanoic acid (S)-3-Amino-4-oxo-4-(((R)-1-oxo-1-((2,2,4,4-tetramethylthietan-3-yl)amino)propan-2-yl)amino)bu (S)-3-((R)-1-(2,2,4,4-TETRAMETHYLTHIETAN-3-YLCARBAMOYL)ETHYLCARBAMOYL)-3-AMINOPROPANOIC ACID Alitame l-alpha-aspartyl-n-(2,2,4,4-tetramethyl-3-thietanyl)-d-alaninamide l-α-aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide CP 54802 (S)-3-AMino-4-oxo-4-(((R)-1-oxo-1-((2,2,4,4-tetraMethylthietan-3-yl)aMino)propan-2-yl)aMino)butanoic acid
- CAS:80863-62-3
- MF:C14H25N3O4S
- MW:331.43
- EINECS:1312995-182-4
- Mol File:80863-62-3.mol
USE
Alitame may be synthesized by a number of routes.For example,
3-(D-alaninamido)-2,2,4,4-tetramethylthietane is dissolved in water
and L-aspartic acid N-thiocarboxyanhydride is then added in
portions with vigorous stirring, maintaining the pH of 8.5–9.5.
The pH is then adjusted to 5.5 and p-toluenesulfonic acid
monohydrate is added over a period of one hour. The precipitated
crystalline p-toluenesulfonate salt is collected by filtration. To
obtain alitame from its salt, a mixture of Amberlite LA-1 (liquid
anion exchange resin), dichloromethane, deionized water, and the
salt is stirred for one hour, resulting in two clear layers. The aqueous
layer is treated with carbon, clarified by filtration, and cooled to
crystallize alitame.<br/>
Alternatively, tetramethylthietane amine is condensed with anNprotected
form of D-alanine to give alanyl amide. This is then
coupled to a protected analogue of L-aspartic acid to give a crude
form of alitame. The crude product is then purified.
Lastest Price from Alitame manufacturers
- Alitame
- US $99.00-35.00/kg
- CAS:80863-62-3
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20ton
- 2024-12-04
- Alitame
- US $10.00 /KG
- CAS:80863-62-3
- Min. Order: 100KG
- Purity: 99%
- Supply Ability: 100 mt
- 2024-11-27
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- Company Name:Shaanxi Pioneer Biotech Co.,Ltd
- Tel:029-029-84385017-8001-8001 18220517932
- Products Intro:Product Name:Alitame
CAS:80863-62-3
Purity:0.98 - CB Index:58
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- Company Name:ChengDu SinoStandards Bio-Tech Co.,Ltd. ,
- Tel:028-83243028 19136088901
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CAS:80863-62-3
Purity:标准品 Package:10mg;100mg;1000mg - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:(S)-3-AMino-4-oxo-4-(((R)-1-oxo-1-((2,2,4,4-tetraMethylthietan-3-yl)aMino)propan-2-yl)aMino)butanoic acid
CAS:80863-62-3
Purity:95+% Package:1g,5g More... - CB Index:76
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:AlitaMe
CAS:80863-62-3
Purity:98% HPLC Package:1g;5g;25g;100g More... - CB Index:69
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- Company Name:Beijing HwrkChemical Technology Co., Ltd
- Tel:010-89508211 18501085097
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CAS:80863-62-3
Purity:98.00% Package:1g - CB Index:55
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- Company Name:Nanjing Chemlin Chemical Co., Ltd
- Tel:025-83697070
- Products Intro:Product Name:Alitame
CAS:80863-62-3
Purity:98% Package:5KG; 1KG More... - CB Index:64
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