BEC
63107-40-4 Basic informationMore
- Product Name:BEC
- Synonyms: BEC S-(2-BORONOETHYL)-L-CYSTEINE L-Cysteine, S-(2-boronoethyl)- (2S)-2-amino-3-(2-boronoethylsulfanyl)propanoic acid Arginase II（BEC hydrochloride） BEC, Arginase inhibitor
- CAS:63107-40-4
- MF:C5H12BNO4S
- MW:193.03
- EINECS:
- Mol File:63107-40-4.mol
-
USE
L-Arginine serves as a common substrate for both nitric oxide synthase (NOS) and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with Nω-hydroxy-L-arginine (NOHA) formed as an intermediate. Arginase, on the other hand, catalyzes the hydrolysis of arginine into urea and L-ornithine. BEC is a potent slow-binding competitive inhibitor of recombinant rat liver arginase I with a Ki of 0.4-0.6 μM. It is also a potent inhibitor of human arginase II with Ki values of 0.31 μM and 30 nM at pH 7.5 and 9.5, respectively. It does not inhibit murine iNOS at concentrations up to 1 mM. BEC significantly enhances NO-dependent relaxation of human penile corpus canvernosum smooth muscle in vitro at concentrations between 0.1-1.0 mM.
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- Company Name:Sigma-Aldrich
- Tel:021-61415566 800-8193336
- Products Intro:Product Name:BEC
CAS:63107-40-4
Purity:>=98% (HPLC) Package:5mg, 25mg Remarks:SML1384 More... - CB Index:80
- Related Information:Catalog(51456)
- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:BEC
CAS:63107-40-4
Purity:98% Package:1mg;5mg;10mg More... - CB Index:58
- Related Information:Catalog(9806)
- Company Name:Wuxi maimo topp biotechnology co., LTD
- Tel: 15061806929
- Products Intro:Product Name:(R)-2-Amino-3-[(2-boronoethyl)thio]propanoic acid
CAS:63107-40-4
Purity:95%;98%;99% Package:0.1g;0.5g;1g;5g;25g;100g;1kg;5kg - CB Index:58
- Related Information:Catalog(5824)
- Company Name:ChemeGen(Shanghai) Biotechnology Co.,Ltd.
- Tel: 18818260767
- Products Intro:Product Name:BEC
CAS:63107-40-4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g - CB Index:58
- Related Information:Catalog(11218)
- Company Name:Shanghai Zeye Biotechnology Co., Ltd.
- Tel:021-61998551 13122364865
- Products Intro:Product Name:BEC hydrochloride
Purity:99.9% Package:1mg/ - CB Index:58
- Related Information:Catalog(9772)