N-ACETYL-4-BENZOQUINONE IMINE
50700-49-7 Basic informationMore
- Product Name:N-ACETYL-4-BENZOQUINONE IMINE
- Synonyms: N-ACETYLBENZOQUINONE-IMINE N-N-Acetyl-4-benzoquinone Imine N-ACETYL-PARA-QUINONEIMINE N-Acetyl-p-benzoquinone imine (NAPQI), 98% 4-(Acetylimino)-2,5-cyclohexadien-1-one N-(4-Oxo-1-cyclohexa-2,5-dienylidene)acetamide, N-Acetyl-p-benzo-quinone imine, NAPQI N-Acetyl-1,4-benzoquinone imine Chebi:29132
- CAS:50700-49-7
- MF:C8H7NO2
- MW:149.15
- EINECS:
- Mol File:50700-49-7.mol
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USE
N-Acetyl-4-benzoquinone imine (NAPQI) is a cytochrome P450 3A4 and 2E1 metabolite of acetaminophen that can be toxic to the liver when acetaminophen is consumed in large doses. At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione. However, following toxic doses of acetaminophen, available liver reserves of glutathione are quickly depleted due to clearance of excess NAPQI, which enables hepatic proteins to become covalently modified by reactive metabolites and eventually results in hepatocyte necrosis.
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:N-Acetyl-4-benzoquinone IMine
CAS:50700-49-7
Package:1Mg,5Mg More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:N-ACETYL-4-BENZOQUINONE IMINE
CAS:50700-49-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15848)
- Company Name:Shanghai Hanhong Scientific Co.,Ltd.
- Tel:021-54306202 13764082696
- Products Intro:Product Name:N-Acetylbenzoquinoneimine
CAS:50700-49-7
Purity:97% Remarks:B36473 More... - CB Index:64
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- Company Name:Shandong Xiya Chemical Co., Ltd
- Tel:4009903999 13355009207
- Products Intro:CAS:50700-49-7
Purity:>=98.0% Package:1mg;5mg - CB Index:57
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- Company Name:ChemStrong Scientific Co.,Ltd
- Tel:0755-0755-66853366 13670046396
- Products Intro:Product Name:N-(4-oxocyclohexa-2,5-dien-1-ylidene)acetamide
CAS:50700-49-7
Purity:95% HPLC Package:10mg;25mg;50mg;100mg - CB Index:56
- Related Information:Catalog(17993)
- Company Name:Shanghai Xingui Biotechnology Co., Ltd.
- Tel: 17501653715
- Products Intro:Product Name:N-ACETYL-4-BENZOQUINONE IMINE
CAS:50700-49-7
Purity:97% Package:100g,500g,1kg,5kg，10kg，25kg…… - CB Index:58
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