M344
251456-60-7 Basic informationMore
- Product Name:M344
- Synonyms: M344 HISTONE DEACETYLASE INHIBITOR III 4-DIMETHYLAMINO-N-(6-HYDROXYCARBAMOYLHEXYL)-BENZAMIDE N-HYDROXY-7-(4-DIMETHYLAMINOBENZOYL)AMINOHEPTANAMIDE 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide, MS 344, D237, N-Hydroxy-7-(4-dimethylaminobenzoyl)-aminoheptanamide 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide MS 344 M 344 (enzyme inhibitor)
- CAS:251456-60-7
- MF:C16H25N3O3
- MW:307.39
- EINECS:
- Mol File:251456-60-7.mol
-
USE
M 344 is an inhibitor of histone deacetylases (HDACs), inhibiting maize HDAC (IC50 = 100 nM) as well as human HDAC1 (IC50 = 46 nM). It shows a three-fold selectivity for inhibition of HDAC6 over HDAC1. M 344 enhances the sensitivity of human squamous carcinoma cells to radiation and promotes cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells (ED50 = 2.3 μM).
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:4-(DiMethylaMino)-N-[7-(hydroxyaMino)-7-oxoheptyl]benzaMide
CAS:251456-60-7
Purity:97.0%(LC) Package:100MG,20MG More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:M 344;4-(DiethylaMino)-N-[7-(hydroxyaMino)-7-oxoheptyl]benzaMide
CAS:251456-60-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386
- Products Intro:Product Name:4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
CAS:251456-60-7
Purity:97.0% LC Package:100MG,20MG More... - CB Index:81
- Related Information:Catalog(24529)
- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel:400-400-6206333 18521732826
- Products Intro:Product Name:M344
CAS:251456-60-7
Purity:>=97% Package:100mg/RMB 1411.90;25mg/RMB 441.90;5mg/RMB 176.90 More... - CB Index:65
- Related Information:Catalog(25003)