ZSTK474
475110-96-4 Basic informationMore
- Product Name:ZSTK474
- Synonyms: 2-(DifluoroMethyl)-1-[4,6-di(4-Morpholinyl)-1,3,5-triazin-2-yl]-1H-benziMidazole 1H-BenziMidazole, 2-(difluoroMethyl)-1-(4,6-di-4-Morpholinyl-1,3,5-triazin-2-yl)- ZSTK474 BASE ZSTK474/ZSTK-474 2-(difluoromethyl)-1-(4,6-dimorpholino-1,3,5-triazin-2-yl)-1H-benzo[d]imidazole 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine ZSTK-474 ZSTK 474 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine ZSTK 474
- CAS:475110-96-4
- MF:C19H21F2N7O2
- MW:417.41
- EINECS:
- Mol File:475110-96-4.mol
-
USE
ZSTK474 is a triazine derivative that acts as an inhibitor of class I phosphatidylinositol 3-kinase (PI3K) isoforms (IC50s = 17, 53, and 6 nM for p110β, -γ, and -δ, respectively). It is selective for PI3K, as it has negligible activity against 139 other kinases when tested at 30 μM. ZSTK474 is orally bioavailable and shows strong antitumor activity against human cancer xenografts in mice. The efficacy of ZSTK474 against certain cancer cells and tumors can be enhanced by combination therapy.
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- Company Name:Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
- Tel:21-57721279
- Products Intro:Product Name:4,4'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine
CAS:475110-96-4
Purity:97% Package:1g,5g,10g,100g,1kg More... - CB Index:56
- Related Information:Catalog(982)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:ZSTK474, 98%
CAS:475110-96-4
Purity:98% Package:10MG;50MG More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:Chembest Research Laboratories Limited
- Tel:021-20908456
- Products Intro:Product Name:2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine
CAS:475110-96-4
Purity:98% HPLC Package:5mg;10mg;50mg;100mg Remarks:Biochemical Reagents; Pharmaceutical Intermediates More... - CB Index:61
- Related Information:Catalog(6011)
- Company Name:Shanghai Longsheng chemical Co.,Ltd.
- Tel:021-58099652-8005 13585536065
- Products Intro:Product Name:ZSTK474
CAS:475110-96-4
Purity:99% More... - CB Index:59
- Related Information:Catalog(9816)
- Company Name:Nanjing Chemlin Chemical Co., Ltd
- Tel:025-83697070
- Products Intro:Product Name:2-(Difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-1H-benzimidazole
CAS:475110-96-4
Purity:98% Package:5KG;1KG More... - CB Index:64
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