BI-6C9

• Product Name:BI-6C9
• Synonyms: N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide Butanamide, N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]- N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide Inhibitor,fission,Neurodegeneration,Bid,BI6C9,BI 6C9,Mitochodondrial,death,Mitochondria,Apoptosis,inhibit,Glutamate,stress,Neuronal,Bcl-2,Mitochondrial,Mitochondrial Metabolism,potential,cell,Oxidative,membrane,BI-6C9,BI-6C-9
• CAS:791835-21-7
• MF:C23H25N3O4S2
• MW:471.59
• EINECS:
• Mol File:791835-21-7.mol
• 

BH3-interacting domain (Bid) is cleaved by caspase-8 to produce the truncated protein tBid, which facilitates cytochrome c release from mitochondria and drives apoptosis. BI-6C9 is an inhibitor of tBid (Kd = 20 μM), blocking the release of both cytochrome c and second mitochondria-derived activator of caspase from mitochondria. It prevents apoptosis in neurons treated with glutamate or oxygen-glucose deprivation. BI-6C9 (10 μM) also inhibits the nuclear translocation of apoptosis-inducing factor AIF, preventing the death of ovarian OVCAR-3 cancer cells induced by IFN-α2a.

• Company Name:Shanghai EFE Biological Technology Co., Ltd.
• Tel:021-65675885 18964387627
• Products Intro:Product Name:BI-6C9
  CAS:791835-21-7
  Purity:98% Package:1mg;2mg;5mg More...
• CB Index:58
• Related Information:Catalog(9806)

• Company Name:Tianjin Kailiqi Biotechnology Co., Ltd.
• Tel: 15076683720
• Products Intro:Product Name:BI-6C9
  CAS:791835-21-7
  Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
• CB Index:55
• Related Information:Catalog(5947)

• Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
• Tel:010-60605840 18892239720
• Products Intro:Product Name:BI-6C9
  CAS:791835-21-7
  Purity:98% Package:5mg;10mg;50mg
• CB Index:58
• Related Information:Catalog(12306)

• Company Name:MedBioPharmaceutical Technology Inc
• Tel:021-69568360 18916172912
• Products Intro:Product Name:BI-6C9
  CAS:791835-21-7
  Purity:98% Package:1mg; 10mg; 5mg Remarks:Medbio
• CB Index:58
• Related Information:Catalog(8140)

• Company Name:Nantong Hi-Future Biotechnology Co., Ltd
• Tel: 18051384581
• Products Intro:Product Name:BI-6C9
  CAS:791835-21-7
  Purity:98% HPLC Package:100mg，500mg，1g，5g，10g
• CB Index:58
• Related Information:Catalog(3021)