Tobramycin sulfate
49842-07-1 Basic informationMore
- Product Name:Tobramycin sulfate
- Synonyms: TOBRAMYCIN SULFATE SALT TOBRAMYCIN SULPHATE 1-epitobramycinsulfate d-6-trideoxy-alpha-d-ribohexopyranosyl-(1-4))-2-deoxysulfate(salt) obracine streptamine,o-3-amino-3-deoxy-alpha-d-glucopyranosyl-(1-6)-o-(2,6-diamino-2,3, tenemicin O-[3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamine sulfate
- CAS:49842-07-1
- MF:C18H39N5O13S
- MW:565.59
- EINECS:256-499-2
- Mol File:49842-07-1.mol
-
USE
Introduced in 1976, tobramycin sulfate (Nebcin) is the mostactive of the chemically related aminoglycosides called nebramycinsobtained from a strain of Streptomyces tenebrarius Five members of the nebramycin complex have beenidentified chemically.<br/>Factors 4 and 4＇ are 6＂-O-carbamoylkanamycin B andkanamycin B, respectively; factors 5＇ and 6 are 6＂-O-carbamoyltobramycinand tobramycin; and factor 2 isapramycin, a tetracyclic aminoglycoside with an unusual bicycliccentral ring structure. Kanamycin B and tobramycinprobably do not occur in fermentation broths per se but areformed by hydrolysis of the 6-O＂-carbamoyl derivatives inthe isolation procedure.<br/>The most important property of tobramycin is its activityagainst most strains of P. aeruginosa, exceeding that of gentamicinby twofold to fourfold. Some gentamicin-resistantstrains of this troublesome organism are sensitive to tobramycin,but others are resistant to both antibiotics. OtherGram-negative bacilli and staphylococci are generally moresensitive to gentamicin. Tobramycin more closely resembleskanamycin B in structure (it is 3＇-deoxykanamycin B).
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- Company Name:Hubei widely chemical technology Co., Ltd.
- Tel:027-83991130 18627774460
- Products Intro:Product Name:Tobramycin Sulphate
CAS:49842-07-1
Purity:99.9% Package:1G 50G 1KG 25KG More... - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:TobraMycin sulfate research grade
CAS:49842-07-1
Package:250MG More... - CB Index:76
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:TobraMycin sulfate
CAS:49842-07-1
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:Spectrum Chemical Manufacturing Corp.
- Tel:021-021-021-67601398-809-809-809 15221380277
- Products Intro:Product Name:TobraMycin sulfate
CAS:49842-07-1
Package:1GM Remarks:BW42010016 More... - CB Index:60
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- Company Name:Alta Scientific Co., Ltd.
- Tel:022-6537-8550 15522853686
- Products Intro:Product Name:Tobramycin sulfate
CAS:49842-07-1
Purity:99% Package:10mg;100mg;1g More... - CB Index:55
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