Warfarin
81-81-2 Basic informationMore
- Product Name:Warfarin
- Synonyms: SAKARAT PROLIN(R) WARF COMPOUND 42(R) WARF(R) Warfarat WARFARIN KYPFARIN(R) DL-3-(ALPHA-ACETONYLBENZYL)-4-HYDROXYCOUMARIN
- CAS:81-81-2
- MF:C19H16O4
- MW:308.33
- EINECS:201-377-6
- Mol File:81-81-2.mol
USE
Warfarin is tasteless and colorless. It is a widely used as anticoagulant (which stops the blood clotting) in the treatment and prevention of thrombosis, in the treatment for chronic atrial fibrillation, mechanical valves, pulmonary embolism, and dilated cardiomyopathy. Warfarin is metabolized primarily via oxidation in the liver by CYP2C9, and exerts its anticoagulant effect by inhibiting the protein vitamin K epoxide reductase complex, subunit 1 (VKORC1). Warfarin therapy can be associated with significant bleeding complications. Achieving a safe therapeutic response can be difficult because of warfarin’s narrow therapeutic index and great individual variability in the dose required, which is mostly a consequence of individual genetic variants: it is influenced by ageing, co-prescribed drugs, diet, alcohol consumption, and comorbid conditions. To maintain a therapeutic level of anti-thrombosis and to minimize the risk of bleeding complications, warfarin therapy requires intensive monitoring via the INR to guide its dosing. It is also used as the first generation of anticoagulant rodenticides.
Lastest Price from Warfarin manufacturers
- Warfarin
- US $1.00 /KG
- CAS:81-81-2
- Min. Order: 0.5KG
- Purity: >99%
- Supply Ability: 20tons
- 2023-05-22
- Warfarin
- US $12.00 /KG
- CAS:81-81-2
- Min. Order: 1Kg/Bag
- Purity: 99%
- Supply Ability: 2kgs
- 2022-09-01
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Warfarin
CAS:81-81-2
Purity:98% HPLC Package:1g;5g;25g;100g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:XiaoGan ShenYuan ChemPharm co,ltd
- Tel: 15527768850
- Products Intro:Product Name:NA
More... - CB Index:52
- Related Information:Catalog(8838)
- Company Name:Shandong Xiya Chemical Co., Ltd
- Tel:4009903999 13355009207
- Products Intro:CAS:81-81-2
Purity:98% Package:25g;100g;500g;1kg More... - CB Index:57
- Related Information:Catalog(18738)
- Company Name:Chengdu Ai Keda Chemical Technology Co., Ltd.
- Tel:4008-755-333 18080918076
- Products Intro:Product Name:Warfarin
CAS:81-81-2
Purity:HPLC;GR;AR;CP Package:5g;25g;100g;500g More... - CB Index:55
- Related Information:Catalog(9718)