Fluphenazine-N-2-chloroethane (hydrochloride)

• Product Name:Fluphenazine-N-2-chloroethane (hydrochloride)
• Synonyms: 10-[3-[4-(2-chloroethyl)-1-piperazinyl]propyl]-2-(trifluoromethyl)-10H-phenothiazinedihydrochloride
• CAS:3892-78-2
• MF:C22H26Cl2F3N3S
• MW:492.4281496
• EINECS:
• Mol File:3892-78-2.mol
• 

<p>Fluphenazine is a traditional antipsychotic compound that tightly binds the dopamine D2 receptor (Ki = 0.55 nM) and also reversibly inhibits calmodulin at micromolar concentrations. Fluphenazine-N-2-chloroethane (hydrochloride) is a derivative of fluphenazine that contains an alkylating chlorethylamine chain, which produces irreversible protein binding. It is a relatively selective, irreversible antagonist of D2 receptors both in vitro (IC50 = 100 nM) and in vivo, inactivating approximately 90% of D2 receptors in mice within 4 hours of treatment. Through this action, fluphenazine-B-2-chloroethane can be used to induce catalepsy in mice. It irreversibly inhibits calmodulin at higher doses (IC50 = 10 μM), which can sensitize cancer cells to TRAIL-induced apoptosis.[Cayman Chemical]</p>

• Company Name:ChemeGen(Shanghai) Biotechnology Co.,Ltd.
• Tel: 18818260767
• Products Intro:Product Name:Fluphenazine-N-2-chloroethane hydrochloride
  CAS:3892-78-2
  Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
• CB Index:58
• Related Information:Catalog(11218)

• Company Name:Shanghai Yifei Biotechnology Co. , Ltd.
• Tel:021-65675885 18964387627
• Products Intro:Product Name:Fluphenazine-N-2-chloroethane (hydrochloride)
  CAS:3892-78-2
  Purity:95% Package:10mg;25mg;50mg
• CB Index:58
• Related Information:Catalog(11974)

• Company Name:TargetMol Chemicals Inc.
• Tel: 15002134094
• Products Intro:Product Name:Fluphenazine-N-2-chloroethane (hydrochloride)
  CAS:3892-78-2
  Package:10mg/RMB 560;25mg/RMB 1100;50mg/RMB 1750
• CB Index:58
• Related Information:Catalog(19703)