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81409-90-7

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81409-90-7 Basic informationMore
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Cabergoline, (6aR,9R,10aR)-7-allyl-N-(3-(dimethylamino)propyl)-N-(ethylcarbamoyl)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide (Dostinex), is a white powder soluble inalcohol, chloroform, and N,N-dimethylformamide; slightlysoluble in acidic solutions and in n-hexane; and insoluble inwater. Following oral administration, peak plasma concentrationsare reached within 2 to 3 hours. Cabergoline ismoderately bound to plasma proteins in a concentrationindependentmanner. The absolute bioavailability of cabergolineis unknown. Cabergoline is extensively metabolizedby the liver, predominantly via hydrolysis of the acylureabond of the urea moiety. CYP450 metabolism appears to beminimal. The major metabolites identified thus far do not contribute to the therapeutic effect of cabergoline. Lessthan 4% is excreted unchanged in the urine. Fecal excretionrepresents the main route of cabergoline elimination. Thereare no reports of interactions of cabergoline with other antiparkinsonianagents. Clarithromycin may elevate theplasma concentration of cabergoline by the inhibition ofboth CYP3A4 and P-glycoprotein.Cabergoline is a potentD<sub>2</sub> receptor agonist and is indicated for the treatment ofhyperprolactinemic disorders, either idiopathic or causedby pituitary adenomas.
Lastest Price from Cabergoline manufacturers
  • Cabergoline
  • US $50.00 /Kg/Bag
  • CAS:81409-90-7
  • Min. Order: 100g
  • Purity: 99.5%
  • Supply Ability: 50tons
  • 2021-04-28
  • Cabergoline
  • US $10.00 /Kg/Drum
  • CAS:81409-90-7
  • Min. Order: 1BOU/Drum
  • Purity: 99%min
  • Supply Ability: 5000
  • 2021-04-21

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  • Company Name:Chengdu mingnijitai Pharmaceutical Co., Ltd
  • Tel:15626879035 156-2687-9035
  • Products Intro:Product Name:Cabergoline
    CAS:81409-90-7
    Purity:99 Package:5018kg
  • CB Index:58
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  • Company Name:Apino Pharma Co., Ltd.
  • Tel:13602565027 0755-23009027-
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    Purity:含量98% 以上 Package:1克;10克;100克;公斤级供货
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  • Company Name:Guangzhou Belka Biological Technology Co., Ltd.
  • Tel:18665676617
  • Products Intro:Product Name:Cabergoline
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    Purity:99% Package:25kg/;1kg/
  • CB Index:58
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  • Company Name:Wuhan Biocar Pharmacy Co.,Ltd
  • Tel:13343447621
  • Products Intro:Product Name:Cabergoline
    CAS:81409-90-7
    Purity:99%
  • CB Index:58
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  • Company Name:Wuhan Biocar Bio-Pharm Co., Ltd.
  • Tel:13343428090
  • Products Intro:Product Name:Cabergoline
    CAS:81409-90-7
    Purity:99 Package:1g/9
  • CB Index:50
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  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Products Intro:Product Name:Cabergoline
    CAS:81409-90-7
    Package:100Mg,10Mg More...
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  • Company Name:Chemvon Biotechnology Co., Ltd
  • Tel:021-50790412
  • Products Intro:Product Name:Cabergoline
    CAS:81409-90-7
    Purity:98% Package:1g, 10g, 100g, 200g, 1kg, 5kg More...
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