UNC 1999
1431612-23-5 Basic informationMore
- Product Name:UNC 1999
- Synonyms: 1H-Indazole-4-carboxamide, N-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]- N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide UNC1999 UNC 1999 UNC1999 UNC-1999 N-[(1,2-Dihydro-6-Methyl-2-oxo-4-propyl-3-pyridinyl)Methyl]-1-(1-Methylethyl)-6-[6-[4-(1-Methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxaMide 1-Isopropyl-6-(6-(4-isopropylpiperazin-1-yl)pyridin-3-yl)-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-1H-indazole-4-carboxamide UNC1999;UNC-1999;UNC 1999
- CAS:1431612-23-5
- MF:C33H43N7O2
- MW:569.74
- EINECS:
- Mol File:1431612-23-5.mol
-
USE
UNC1999 is highly potent for both EZH2 Y641N and EZH2 Y641F mutants in vitro. UNC1999 causes concentration-dependent reductions of H3K27me3 in MCF10A cells with IC50 of 124 nM , while shows low cellular toxicity. UNC1999 displays potent, concentration-dependent inhibition of cell proliferation with EC50 of 633 nM in a DLBCL cell line harboring the EZH2Y641N mutant. In addition, biotinylated UNC1999 enriches EZH2 from HEK293T cell lysates, and thus may be used in chemoproteomics studies.
Lastest Price from UNC 1999 manufacturers
- UNC1999
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- US $0.00-0.00/KG
- CAS:1431612-23-5
- Min. Order: 5mg
- Purity: 99%HPLC
- Supply Ability: 2000tons
- 2024-02-01
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:UNC1999
CAS:1431612-23-5
Package:25Mg,5Mg More... - CB Index:76
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- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
- Products Intro:Product Name:UNC 1999
CAS:1431612-23-5
Purity:>98%,BR Package:5MG;25MG; Remarks:MB3194 - CB Index:58
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- Company Name:UHN Shanghai Research & Development Co., Ltd.
- Tel:021-58958002 18930822973
- Products Intro:Product Name:UNC1999
CAS:1431612-23-5
Purity:98% LC-MS Package:10g, 50g, 100g, 1Kg Remarks:B100831 More... - CB Index:58
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- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
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- Products Intro:Product Name:UNC1999
CAS:1431612-23-5
Purity:10mM in DMSO Package:1ml/RMB 720.90 More... - CB Index:65
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