RN486

• Product Name:RN486
• Synonyms: RN486 6-cyclopropyl-8-fluoro-2-(2-(hydroxyMethyl)-3-(1-Methyl-5-((5-(4-Methylpiperazin-1-yl)pyridin-2-yl)aMiNA)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)isoquiNAlin-1(2H)-one 6-cyclopropyl-8-fluoro-2-(2-(hydroxyMethyl)-3-(1-Methyl-5-(5-(4-Methylpiperazin-1-yl)pyridin-2-ylaMino)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)isoquinolin-1(2H)-one RN486/RN-486 RN468 6-Cyclopropyl-2-[3-[1,6-dihydro-1-methyl-5-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]-6-oxo-3-pyridinyl]-2-(hydroxymethyl)phenyl]-8-fluoro-1(2H)-isoquinolinone RN486 LM-2078 RN486 TFA Salt
• CAS:1242156-23-5
• MF:C35H35FN6O3
• MW:606.69
• EINECS:200-110-4
• Mol File:1242156-23-5.mol
• 

RN486 displays similar functional activities in rodent models, effectively preventing type I and type III hypersensitivity responses. More importantly, RN486 produces robust anti-inflammatory and bone-protective effects in mouse CIA and rat adjuvant-induced arthritis (AIA) models. In the AIA model, RN486 inhibits both joint and systemic inflammation either alone or in combination with methotrexate, reducing both paw swelling and inflammatory markers in the blood.

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:RN 486(RN-486)
  CAS:1242156-23-5
  Purity:98%+ HPLC Package:50mg;100mg;500mg;1g;5g;10g Remarks:Biochemical Reagents; Pharmaceutical Intermediates More...
• CB Index:61
• Related Information:Catalog(6005)

• Company Name:Wuhan Kaymke Chemical Co., Ltd.,
• Tel:027-027-87342388 18086026008
• Products Intro:Product Name:RN486
  CAS:1242156-23-5
  Purity:97% HPLC Package:1g;5g;10g;25;50g More...
• CB Index:55
• Related Information:Catalog(3864)

• Company Name:Suzhou yacoo science co.,Ltd
• Tel:0512-87182056 18013166090
• Products Intro:Product Name:RN486
  CAS:1242156-23-5
  Purity:98% Package:10g;50g;1kg;5Kg;25kg;
• CB Index:60
• Related Information:Catalog(7295)