MonoMethyl auristatin E
474645-27-7 Basic informationMore
- Product Name:MonoMethyl auristatin E
- Synonyms: MonoMethyl auristatin E(MMAE, vedotin) HM-297C-22 MonoMethyl auristatin E Monomethyl auristatin E, >=98% MMAE(Monomethyl auristatin E) (2S)-N-[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-3-methyl-2-(methylamino)butanamide [3H]-Vedotin (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1R,2R)-1-Hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy
- CAS:474645-27-7
- MF:C39H67N5O7
- MW:717.98
- EINECS:
- Mol File:474645-27-7.mol
USE
Dolastatin 10 is a natural antimitotic and antineoplastic agent that binds to tubulin and inhibits tubulin polymerization. Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity. MMAE is typically coupled to the antibody via a protease-cleavable linker, allowing separation of the drug from the antibody following intracellular localization.[Cayman Chemical]
Lastest Price from MonoMethyl auristatin E manufacturers
- MonoMethyl auristatin E
- US $30.00 /kg
- CAS:474645-27-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000t/year
- 2023-09-07
- MonoMethyl auristatin E
- US $0.00 /KG
- CAS:474645-27-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- 2023-06-29
Browse by Nationality 474645-27-7 Suppliers >Global suppliers
Beijing (11) Shanghai (74) Tianjin (3) Chongqing (1) Sichuan (3) Guangdong (9) Zhejiang (18) Fujian (1) Hunan (3) Hubei (52) Shandong (21) Henan (11) Hebei (5) Jilin (3) Liaoning (1) Anhui (7) Jiangsu (39) Jiangxi (7) Shaanxi (4) Hong Kong (2) Other (1) Member (275) All (276)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Zhejiang Huida Biotech Co., LTD
- Tel:0571-89903882 15990081639
- Products Intro:Product Name:MMAE
CAS:474645-27-7
Purity:99% HPLC Package:10mg;100mg;1g;10g;100g;1kg;10kg;100kg - CB Index:58
- Related Information:Catalog(3656)
- Company Name:Shanghai Send Pharmaceutical Technology Co., Ltd.
- Tel:+86-021-50266790 Q2816483246
- Products Intro:Product Name:MonoMethyl auristatin E
CAS:474645-27-7
Purity:98% Package:1g/kg;100g/kg;1000g/kg - CB Index:50
- Related Information:Catalog(199)
- Company Name:Shanghai Linka Biotechnology Co., Ltd.
- Tel: 15901858719
- Products Intro:Product Name:MONOMETHYL AURISTATIN E
CAS:474645-27-7
Purity:0.98 Package:10g;100g;1kg;5kg;25kg Remarks:10g;100g;1kg;5kg;25kg More... - CB Index:55
- Related Information:Catalog(311)
- Company Name:Tianjin Chempharmatech Co.,Ltd.
- Tel:022-66211079 13212288319
- Products Intro:Product Name:Monomethyl auristatin E
CAS:474645-27-7
Purity:98% HPLC Package:1g;5g;10g;25g;100g;1kg More... - CB Index:55
- Related Information:Catalog(879)
- Company Name:Shanghai ruichang pharmaceutical technology co., LTD
- Tel: 18621054990
- Products Intro:Product Name:MonoMethyl auristatin E
CAS:474645-27-7
Purity:0.95 Package:25mg, 50mg, 100mg, 1g More... - CB Index:58
- Related Information:Catalog(673)
- Company Name:Abydos Scientific
- Tel:025-84767922 18936879710
- Products Intro:Product Name:MMAE
CAS:474645-27-7
Purity:0.99 Package:500g;100g;10g;1g - CB Index:58
- Related Information:Catalog(1010)
- Company Name:Shanghai Haoyuan Chemexpress Co., Ltd.
- Tel:021-51870955
- Products Intro:Product Name:MMAE
CAS:474645-27-7
Purity:≥99% Package:1g;10g;100g - CB Index:58
- Related Information:Catalog(817)
- Company Name:ACROBiosystems
- Tel: 18514007688
- Products Intro:Product Name:MMAE
CAS:474645-27-7
- CB Index:58
- Related Information:Catalog(1212)