N-OXALYL GLYCINE
5262-39-5 Basic informationMore
- Product Name:N-OXALYL GLYCINE
- Synonyms: N-OXALYL GLYINE 2-((Carboxymethyl)amino)-2-oxoacetic acid SYM1 SYNS1 N-OXALYL GLYCINE NOG Glycine,N-(carboxycarbonyl)- Human NOG Protein, His Tag
- CAS:5262-39-5
- MF:C4H5NO5
- MW:147.09
- EINECS:
- Mol File:5262-39-5.mol
-
USE
The jumonji domain-containing protein 2 (JMJD2) subfamily of histone demethylases have been shown to catalyze demethylation of the methylated forms of histone 3 lysine 9 (H3K9) and H3K36 in vitro and in cells. Because histone demethylases are implicated in certain diseases, including cancer, selective inhibitors are candidate anticancer agents as well as potential tools for elucidating the biological functions of JMJDs. N-Oxalylglycine, the amide analog of α-ketoglutarate, is a cell permeable inhibitor of α-ketoglutarate-dependent enzymes, including JMJD2A, JMJD2C, and JMJD2E (IC50s = 250, 500, and 24 μM, respectively). It can also inhibit the prolyl hydroxylase domain-containing proteins PHD1 and PHD2 with IC50 values of 2.1 and 5.6 μM, respectively.[Cayman Chemical]
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- Company Name:Shanghai Thunder Biological Technology Co., Ltd.
- Tel: 18621609968
- Products Intro:Product Name:N-OXALYL GLYCINE
CAS:5262-39-5
Purity:97% Package:100g/;200g/;500g/ - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:N-Oxalyl glycine
CAS:5262-39-5
Purity:98% Package:100Mg,1g,500Mg More... - CB Index:76
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- Company Name:Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
- Tel:028-85114309 15881143215
- Products Intro:Product Name:N-OXALYL GLYCINE
CAS:5262-39-5
Purity:97% Package:5g/;10g/ - CB Index:55
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- Company Name:Bide Pharmatech Ltd.
- Tel:400-1647117 15221909166
- Products Intro:Product Name:2-((Carboxymethyl)amino)-2-oxoacetic acid
CAS:5262-39-5
Purity:98% Package:100mg;250mg;1g;5g; More... - CB Index:60
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- Company Name:Finetech Industry Limited
- Tel:027-87465837 19945049750
- Products Intro:Product Name:N-OXALYL GLYCINE
CAS:5262-39-5
Purity:98% Package:1g,10g,25g,500g,1kg - CB Index:58
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- Company Name:Sichuan Ampebiochem Co., Ltd.
- Tel:028-65294243
- Products Intro:Product Name:N-OXALYL GLYCINE
CAS:5262-39-5
Purity:98% HPLC Package:50g;1kg;10kg;100kg More... - CB Index:58
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- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:N-Oxalylglycine
CAS:5262-39-5
Purity:98% (1H-NMR) Package:5mg;10mg;50mg More... - CB Index:58
- Related Information:Catalog(9709)