MYRIOCIN
35891-70-4 Basic informationMore
- Product Name:MYRIOCIN
- Synonyms: MYRIOCIN MYRIOCIN, MYCELIA STERILIA THERMOZYMOCIDIN 6e))-4s* 6-eicosenoicacid,2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-,(2s-(2r*,3s [2S,3R,4R,6E]-2-AMINO-3,4-DIHYDROXY-2-[HYDROXYMETHYL]-14-OXO-6-EICOSENOIC ACID [2S,3R,4R]-(E)-2-AMINO-3,4-DIHYDROXY-2-[HYDROXYMETHYL]-14-OXO-6-EICOSENOIC ACID ISP-I
- CAS:35891-70-4
- MF:C21H39NO6
- MW:401.54
- EINECS:636-862-5
- Mol File:35891-70-4.mol
-
USE
Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A. Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. It disrupts substratum adhesion of melanoma cells. It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis. Myriocin suppresses replication of the hepatitis C virus in a murine model.[Cayman Chemical]
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Myriocin, 99%, from Mycelia sterilia
CAS:35891-70-4
Purity:99% Package:5MG More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel:400-400-6206333 18521732826
- Products Intro:Product Name:Myriocin
CAS:35891-70-4
Purity:98% Package:25mg/RMB 4737.90;5mg/RMB 1076.90;1mg/RMB 368.90 More... - CB Index:65
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- Company Name:Shanghai Tauto Biotech Co., Ltd.
- Tel:021-51320588
- Products Intro:Product Name:Myriocin
CAS:35891-70-4
Purity:NLT 95% HPLC Package:10Mg;20Mg;50Mg;100Mg to graMs.Not More than tens of graMs. Remarks:M9634 More... - CB Index:66
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- Company Name:TargetMol Chemicals Inc.
- Tel:021-021-33632979 15002134094
- Products Intro:Product Name:Myriocin
CAS:35891-70-4
Purity:100% Package:2mg/RMB 987;5mg/RMB 1730 - CB Index:58
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- Company Name:ChemStrong Scientific Co.,Ltd
- Tel:0755-0755-66853366 13670046396
- Products Intro:Product Name:Myriocin
CAS:35891-70-4
Purity:95% HPLC Package:10mg;25mg;50mg More... - CB Index:56
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- Company Name:Sigma-Aldrich
- Tel:021-61415566 800-8193336
- Products Intro:Product Name:Myriocin
CAS:35891-70-4
Purity:>= 98 % HPLC, powder Package:5mg, 25mg Remarks:M1177 More... - CB Index:80
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