3-(4-Pyridyl)indole
7272-84-6 Basic informationMore
- Product Name:3-(4-Pyridyl)indole
- Synonyms: 3-(4-Pyridinyl)- Rho Kinase Inhibitor III, Rockout 1H-Indole, 3-(4-pyridinyl)- 3-(4-Pyridinyl)-1H-indole 3-(4-Pyridyl)indole Rho Kinase Inhibitor III, Rockout - CAS 7272-84-6 - Calbiochem Rho Kinase Inhibitor III RHO KINASE INHIBITOR III; ROCK INHIBITOR III; ROCKOUT
- CAS:7272-84-6
- MF:C13H10N2
- MW:194.23
- EINECS:
- Mol File:7272-84-6.mol
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USE
Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. 3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 μM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay. It also inhibits ROCK-II and PRK2, another Rho-dependent kinase, with similar potency, while inhibiting MSK-1 and PKA with relatively weaker potency.[Cayman Chemical]
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:3-(4-Pyridyl)indole
CAS:7272-84-6
Package:250Mg,25Mg More... - CB Index:76
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- Company Name:Sigma-Aldrich
- Tel:021-61415566 800-8193336
- Products Intro:Product Name:Rho Kinase Inhibitor III, Rockout - CAS 7272-84-6 - Calbiochem
- CB Index:80
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- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:3-(4-Pyridyl)indole
CAS:7272-84-6
Purity:98% Package:5mg;10mg;25mg More... - CB Index:58
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- Company Name:Biokitchen
- Tel:021-021-021-31663258 13795219287
- Products Intro:Product Name:1H-Indole, 3-(4-pyridinyl)-
CAS:7272-84-6
Purity:> 97% HPLC Package:10G;100G；500G；1KG; 5KG, 10KG; 100KG More... - CB Index:58
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- Company Name:Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel:+86-400-002-6226 +86-13028896684;
- Products Intro:Product Name:3-(4-Pyridyl)indole
CAS:7272-84-6
More... - CB Index:58
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- Company Name:Career Henan Chemica Co
- Tel:+86-0371-86658258 +8613203830695
- Products Intro:Product Name:3-(4-Pyridyl)indole
CAS:7272-84-6
Purity:99% Package:1g;0.37USD - CB Index:58
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- Company Name:DC Chemicals
- Tel:021-58447131 13564518121
- Products Intro:Product Name:3-(4-Pyridyl)
CAS:7272-84-6
Purity:98% HPLC Package:100mg，250mg，1g More... - CB Index:58
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