Udenafil

• Product Name:Udenafil
• Synonyms: Benzenesulfonamide, 3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-N-(2-(1-methyl-2-pyrrolidinyl)ethyl)-4-propoxy- Da 8159 Da-8159 3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-propoxybenzenesulfonamide Udenafil Udenafi 3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxybenzenesulfonamide 5-[2-propyloxy-5-(2-(1-Methylpyrrolidin-2-yl)ethylaMinosulphonyl)phenyl]-1-Methyl-3-propyl-6,7-dihydro-1H-pyrazolo(4,3-d)pyriMidin-7-one
• CAS:268203-93-6
• MF:C25H36N6O4S
• MW:516.66
• EINECS:251-228-4
• Mol File:268203-93-6.mol
• 

Udenafil is the fourth in a class of drugs targeting the inhibition of the enzyme phosphodiesterase 5 (PDE5) for the treatment of erectile dysfunction. Inhibition of PDE5 results in the increase in endogenous cyclic guanosine monophosphate (cGMP) concentrations in the penile corpus cavernosum. cGMP induces smooth muscle cell relaxation and subsequent increased blood flow leading to a sustainable erection. Udenafil is a potent antagonist of human PDE5 with an IC₅₀ of 8.25nM and a comparable selectivity profile as sildenafil for the other PDEs. Unlike tadalafil, it does not inhibit PDE11, which has been implicated in myalgia and testicular toxicity. Furthermore, udenafil produced up to a 91% vaginal penetration success rate and up to a 67% intercourse completion rate compared to a 29% completion rate by placebo. Overall patient satisfaction, measured by a standard global assessment question, was 86% compared to only 26% in the placebo group. The most frequently recorded adverse events were mild-to-moderate facial flushing and headache.

• Udenafil
• 
• US $40.00 /kg
• CAS:268203-93-6
• Min. Order: 1kg
• Purity: 0.99
• Supply Ability: 10 tons
• 2024-10-25

• Udenafil
• 
• US $30.00 /kg
• CAS:268203-93-6
• Min. Order: 1kg
• Purity: 99%
• Supply Ability: 1000t/year
• 2023-09-11

• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:Udenafil
  CAS:268203-93-6
  Package:100Mg,10Mg More...
• CB Index:76
• Related Information:Catalog(94657)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:Udenafil(DA 8159,Zydena)
  CAS:268203-93-6
  Remarks:C14303 More...
• CB Index:61
• Related Information:Catalog(6005)

• Company Name:Adamas Reagent, Ltd.
• Tel:400-6009262 16621234537
• Products Intro:Product Name:3-(6,7-Dihydro-1-Methyl-7-Oxo-3-Propyl-1H-Pyrazolo[4,3-d]Pyrimidin-5-yl)-N-[2-(1-Methyl-2-Pyrrolidinyl)Ethyl]-4-Propoxybenzenesulfonamide
  CAS:268203-93-6
  Purity:98%+ Package:25mg;100mg;250mg;1g;5g
• CB Index:59
• Related Information:Catalog(14103)

• Company Name:Beijing Yisiyan Technology Research Center
• Tel:010-56645598 13366904824
• Products Intro:Product Name:5-[2-propyloxy-5-[2-(1-Methyl-2-pyrrolidinyl)ethylaMinosulfonyl]phenyl]-1-Methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyriMidine-7-one
  CAS:268203-93-6
  Purity:>98% Package:10g;50g;500g More...
• CB Index:59
• Related Information:Catalog(1637)

• Company Name:Guangzhou Isun Pharmaceutical Co., Ltd
• Tel:020-39119399 18927568969
• Products Intro:Product Name:Udenafil
  CAS:268203-93-6
  Purity:98.0% Package:1G; 25G; 1KG; 25KG
• CB Index:55
• Related Information:Catalog(4428)

• Company Name:Bide Pharmatech Ltd.
• Tel:400-164-7117 13681763483
• Products Intro:Product Name:3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-propoxybenzenesulfonamide
  CAS:268203-93-6
  Purity:98% Package:100mg;250mg;1g; Remarks:BD227977
• CB Index:60
• Related Information:Catalog(41462)