アンジオテンシン変換酵素 ウサギ肺由来 Angiotensin Converting Enzyme from rabbit lung
Sigma-Aldrich Japan
Z568880
1EA
￥23000
Aceプレッシャーチューブ
Sigma-Aldrich Japan
Z568767
1EA
￥21900
Aceプレッシャーチューブ
Sigma-Aldrich Japan
Z568775
1EA
￥21800
Aceプレッシャーチューブ
Sigma-Aldrich Japan
Z566241
1EA
￥21100
Aceプレッシャーチューブ
Sigma-Aldrich Japan
A6778
0.1unit
￥18800
アンジオテンシン変換酵素 ウサギ肺由来 Angiotensin Converting Enzyme from rabbit lung
Sigma-Aldrich Japan
Z568783
1EA
￥17900
Aceプレッシャーチューブ
Sigma-Aldrich Japan
Z568821
1EA
￥26300
Aceプレッシャーチューブ
Sigma-Aldrich Japan
Z568813
1EA
￥26100
Aceプレッシャーチューブ
1of4
プロパティ
貯蔵温度
-20°C
外見
lyophilized powder
色
Off-white to light yellow
Specific Activity
≥2.0units/mg protein (modified Warburg-Christian)
安全情報
絵表示(GHS)
注意喚起語
Danger
危険有害性情報
H334：吸入するとアレルギー、喘息または、呼吸困難 を起こすおそれ
注意書き
P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。
P284：呼吸用保護具を着用すること。
P501：内容物/容器を．．．に廃棄すること。
説明
ACE possesses dual actions to convert Ang I to Ang II,
and degrade bradykinin. The development of an ACE inhibitor was the first effective drug for hypertension caused by
high renin activity. ACE2 was identified as the receptor
for the SARS (severe acute respiratory syndrome) coronavirus, which caused an epidemic in 2002–2003. ACE was discovered in the mid-1950s through the
observation that the dialysis of plasma and kidney extract
with water and saline before incubation produced two separate pressor substances, Ang I and Ang II, respectively. It
was discovered for a second time in 1966 during the characterization of a bradykinin (BK)-degrading enzyme from
the kidney. This was named kininase II, which later was
found to be the same enzyme as ACE. ACE2 was discovered in 2000 when two independent research groups
cloned homologous ACE that could convert Ang I to
Ang1–9 and yet also be captopril-insensitive.
