Propargyl-PEG7-t-butyl ester comprises a propargyl group and a t-butyl protected carboxyl group. The propargyl group reacts with azide compounds via copper catalyzed Click Chemistry to form a stable triazole linkage. Under acidic conditions, the carboxyl group can be deprotected. The hydrophilic PEG units enhance solubility of the molecule in aqueous media.