Talc suppliers

Talc

CAS:: 14807-96-6

MF:: 3MgO.4O2Si.H2O

MW:: 379.263

SecurityInformation

Symbol(GHS) ：: GHS07

Signal word ：: Warning

Hazard statements ：: H332

Precautionary statements ：: P261-P271-P304+P340-P312a

Hazard Codes ：: Xn

Risk Statements ：: 20-37

Safety Statements ：: 36

OEB：: B

OEL：: TWA: 2 mg/m3 (resp)

WGK Germany ：: -

RTECS ：: WW2710000

TSCA ：: Yes

HS Code ：: 25262020

Toxicity：: A finely powdered hydrous magnesium silicate. It is used in a variety of industrial processes and products, including rubber, paints, lubricants, insulating materials, cosmetics, and toiletries, such as baby and dusting powders. Acute inhalation of large quantities of talc, such as infants aspirating a massive amount of powder, has caused death within hours because of drying of the mucous membranes, clogging of the smaller airways, pulmonary edema and pneumonia. Chronic inhalation of talc, such as occurs in talc miners, leads to talcosis (a pneumoconiosis) involving pulmonary fibrosis and pleural sclerosis. Lymph nodes can also be affected. There are suggestions that talc can result in cervical or ovarian cancer although evidence for this is not extensive. Some talc is contaminated with asbestos.

IDLA：: 1,000 mg/m3

Use：: Talc is used mainly in tablet and capsule formulations. Talc is not absorbed systemically following oral ingestion and is therefore regarded as an essentially nontoxic material. However, intranasal or intravenous abuse of products containing talc can cause granulomas in body tissues, particularly the lungs. Contamination of wounds or body cavities with talc may also cause granulomas; therefore, it should not be used to dust surgical gloves. Inhalation of talc causes irritation and may cause severe respiratory distress in infants. Although talc has been extensively investigated for its carcinogenic potential, and it has been suggested that there is an increased risk of ovarian cancer in women using talc, the evidence is inconclusive. However, talc contaminated with asbestos has been proved to be carcinogenic in humans, and asbestos-free grades should therefore be used in pharmaceutical products. Also, long-term toxic effects of talc contaminated with large quantities of hexachlorophene caused serious irreversible neurotoxicity in infants accidentally exposed to the substance.

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Yujiang Chemical (Shandong) Co.,Ltd.