Ramatroban suppliers

Ramatroban

CAS:: 116649-85-5

MF:: C21H21FN2O4S

MW:: 416.47

Use：: Ramatroban, originally developed for the treatment of cardiovascular pathologies as thromboembolism, was finally introduced in Japan for the treatment of allergic rhinitis. It is a (3R)-enantiomer that can be synthesized in 5 steps from 3-oxo-1,2,3,4- tetrahydrocarbazole by stereoselective reductive amination, using S-phenethylamine as the chiral source, followed by hydrogenolysis, sulfonylation and finally 2-step Ncarboxyethylation. Ramatroban is a potent antagonist of prostaglandin receptors (PGD2, PGH2) and thromboxane receptors (TxA2); accordingly, it blocks the contractions induced by thromboxane or TxA2-mimetics in animal and human airway smooth muscle. It also prevents, when administered i.v., p.o. or by aerosol, bronchoconstriction induced by PGD2 or antigen. In animal models of nasal allergy, ramatroban inhibits antigen-induced neutrophil infiltration into nasal mucosa and also inhibits nasal symptoms. In several species including humans, it is well-absorbed, extensively protein-bound (>95%) and eliminated mainly as a glucuro-conjugate; in man, its terminal half-life is 2 to 3 hours.

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You can find Ramatroban suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Ramatroban
Remarks: Purity: More Than 99% | Package: 1g
TEL: 010-87925929
CHINA Trader

￥0.00/1g

Capot Chemical Co.,Ltd.

(R)-3-(3-(4-fluorophenylsulfonamido)-3,4-dihydro-1H-carbazol-9(2H)-yl)propanoic acid
Remarks: Purity: 98%(Min GC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
TEL: 571-85586718
CHINA Trader

Hangzhou FandaChem Co.,Ltd.

Ramatroban
CHINA Trader

career henan chemical co

Ramatroban
Remarks: Purity: 98% | Package: 1KG;15USD
TEL: 0371-86658258
CHINA Reagent

￥15.00/1KG

BOC Sciences

Ramatroban
Remarks: Purity: >98% | Package: 100mg | CustNote: BOC Sciences also provides custom synthesis services for Ramatroban.
UNITED STATES Trader

CONIER CHEM AND PHARMA LIMITED

ramatroban
Remarks: Purity: 99% | Package: 1kg
CHINA Trader

SIMAGCHEM CORP

Ramatroban
Remarks: Purity: 0.99 | Package: 1kg,5kg,25kgs,200kgs;bulk
CHINA Trader

TargetMol Chemicals Inc.

Ramatroban；BAY u3405
Remarks: Purity: 99.96% | Package: 5mg;32USD|10mg;52USD|25mg;96USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

AFINE CHEMICALS LIMITED

RAMATROBAN
Remarks: Purity: 99% | Package: USP EP CP
TEL: 0571-85134551
CHINA Trader

Baoji Guokang Bio-Technology Co., Ltd.

Ramatroban
Remarks: Purity: 0.98 | Package: 1KG；500G
TEL: 0917-3909592
CHINA Trader