PROTEIN C suppliers

PROTEIN C

CAS:: 42617-41-4

MF:

MW:: 0

Use：: Drotrecogin alfa was introduced in the US as a new intravenous treatment for the reduction of mortality in adult patients with severe sepsis associated with acute organ dysfunction. Drotrecogin aifa is the first recombinant activated protein C expressed in human kidney 293 cells. Activated protein C1 an endogenous serine protease, acts as an antithrombotic via inhibition of factor Va and Vllla, promotes fibrinolysis via inactivation of plasminogen-activator inhibitor-1 and exerts an anti-inflammatory effect by inhibiting the production of inflammatory cytokines (tumor necrosis factor-alpha, interieukin-1 and 6) by monocytes. It was shown that the majority of patients with sepsis have reduced levels of activated protein C. In a baboon model of lethal E. coli sepsis, administration of activated protein C reduced mortality. In a phase III clinical trial, intravenous infusion of drotrecogin alfa at a dose of 24 μg/kg/h over 96 h significantly reduced the risk of death compared with placebo in patients with severe sepsis. However, an increased risk of serious bleeding has been associated with the administration of the drug.

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You can find PROTEIN C suppliers, manufacturers, and distributors from countries such as United States, China and the Japan here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Shanghai Huzhen Industrial Co., LTD

protein C
Remarks: Purity: > 99% | Package: 50ul/RMB 1138;100ul/RMB 1880;200ul/RMB 2900 | CustNote: Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; EC 3.4.21.69; PC; PROC; PROC1; Vitamin K dependent protein C precursor; APC; EC 3.4.21.69; PC; proC; PRO
CHINA Service provider

Sigma-Aldrich Co. LLC.

ProteinC from human plasma
Remarks: Brand: Sigma-Aldrich | Product Number: P2200 | Purity: Activated, lyophilized powder, ≥90% (SDS-PAGE)
TEL: 800 558-9160
UNITED STATES Trader

￥447.00/.1mg

Sigma-Aldrich Chemicals Private Limited

Anti-APC(C-terminal)antibodyproducedinrabbit
Remarks: Brand:sigma aldrich | Product Number:SAB4200594 | Purity:~1.0?mg/mL,affinityisolatedantibody
TEL: 1-800-309-6000
INDIA Trader

United States Biological

Protein C
Remarks: Brand：Usbio | OriginalID：156493
TEL: 800.520.3011 or 781.639.5092
UNITED STATES Trader

￥360.00/10ug

EMD Biosciences, Inc.

PROTEIN C
TEL: 858 450 5500
UNITED STATES Trader

VWR International

PROTEIN C
TEL: 800 932 5000
UNITED KINGDOM Trader

Wako Pure Chemical Industries, Ltd.

PROTEIN C
TEL: +81 6 6203 3741
JAPAN Trader

BIOTREND Chemikalien GmbH

PROTEIN C
TEL: 49 (0) 221 949 83 20
GERMANY Trader

Kanto Chemical Co., Inc.

PROTEIN C
TEL: +81 3 3663 7631
JAPAN Trader

SIGMA-RBI

PROTEIN C
TEL: 800 736 3690 (Orders)
SWITZERLAND Trader