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Pemoline suppliers
- CAS:
- 2152-34-3
- MF:
- C9H8N2O2
- MW:
- 176.17
Properties
- Melting point:：
- 255-256°C
- Boiling point:：
- 307.77°C (rough estimate)
- Density ：
- 1.2662 (rough estimate)
- refractive index ：
- 1.5570 (estimate)
- storage temp. ：
- Store at RT
- solubility ：
- DMSO: soluble28mg/mL
- form ：
- solid
- pka：
- pKa 10.5 (Uncertain)
- color ：
- white
SecurityInformation
- Symbol(GHS) ：
-
GHS07
- Signal word ：
- Warning
- Hazard statements ：
- H302+H312+H332
- Precautionary statements ：
- P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
- Hazard Codes ：
- Xn,C,F,T
- Risk Statements ：
- 22-34-11-20/21/22
- Safety Statements ：
- 16-26-36/37/39-45-36/37-36
- WGK Germany ：
- 3
- RTECS ：
- PB8750000
- Toxicity：
- LD50 orally in rats: 500 mg/kg (Schafer)
- Use：
- Pemoline, 2-amino-5-phenyl-4(5H)-oxazolone (Cylert), hasa unique structure.The compound is described as having an overall effect onthe CNS like that of methylphenidate. Pemoline requires 3to 4 weeks of administration, however, to take effect. A partialexplanation for the delayed effect may be that one of theactions of the agent, as observed in rats, is to increase therate of synthesis of DA.
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