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ChemicalBook >> CAS DataBase List >>Olopatadine hydrochloride

Olopatadine hydrochloride suppliers

Olopatadine hydrochloride

CAS:: 140462-76-6

MF:: C21H24ClNO3

MW:: 373.88

SecurityInformation

Symbol(GHS) ：: GHS06,GHS09

Signal word ：: Danger

Hazard statements ：: H301-H400

Precautionary statements ：: P273-P301+P310+P330

Hazard Codes ：: T,N

Risk Statements ：: 25-50

Safety Statements ：: 45-61

RIDADR ：: UN 2811 6.1 / PGIII

WGK Germany ：: 3

RTECS ：: HQ4135060

HS Code ：: 29329990

Use：: Olopatadine hydrochloride is a potent, selective antagonist of the H1 histamine receptor (Ki = 16-41.1 nM), with much lower affinities for the H2 and H3 receptors (Ki = 43.4 and 172 μM, respectively). It blocks histamine-induced phosphoinositide turnover in isolated cells (IC50 = 9.5-39.9 nM) and prevents passive cutaneous anaphylaxis in rats (ED50 = 49 μg/kg) and anaphylactic bronchoconstriction in guinea pigs (ID50 = 30 μg/kg). Olopatadine is effective in treating allergic rhinitis and conjunctivitis. It also suppresses itch in patients with well-controlled chronic urticaria. In humans, this antihistamine does not cause cognitive or psychomotor impairment at therapeutic doses.[Cayman Chemical]

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You can find Olopatadine hydrochloride suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Guangzhou Tosun Pharmaceutical Ltd