NPS 2390 suppliers

NPS 2390

CAS:: 226878-01-9

MF:: C19H21N3O

MW:: 307.39

Use：: Metabotropic glutamate receptors (mGluRs), mediate excitatory synaptic transmission in the central nervous system. Potent and selective antagonists of the type I mGluRs (mGluR1 and mGluR5) are of interest as novel therapeutics for the treatment of various CNS disorders, such as pain, epilepsy, and stroke. NPS 2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 with IC50 values equal to 5.2 and 82 nM, respectively). At concentrations up to 30 μM, NPS 2390 does not affect mGluR2 or mGluR8 or a standard collection of 37 additional receptors, ion channels, and enzymes. At a dose of 10 mg/kg, NPS 2390 displaced the specifically bound mGlu1R-selective antagonist, [3H]R214127, in rat cerebellum.

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You can find NPS 2390 suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

ATK CHEMICAL COMPANY LIMITED

NPS 2390
Remarks: Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
TEL: 21-51877795
CHINA Reagent

Aladdin Scientific

NPS 2390
Remarks: Purity: >=99%(HPLC) | Package: $73.9/5mg;$117.9/10mg;$226.9/25mg;$395.9/50mg;$642.9/100mg;$1446.9/250mg;Bulk pa | CustNote: 99%(HPLC)
TEL: +1(833)-552-7181
UNITED STATES Trader