Malononitrile suppliers

Malononitrile

CAS:: 109-77-3

MF:: C3H2N2

MW:: 66.06

SecurityInformation

Symbol(GHS) ：: GHS06,GHS09

Signal word ：: Danger

Hazard statements ：: H300-H311+H331-H317-H319-H410

Precautionary statements ：: P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P305+P351+P338

Hazard Codes ：: T,N

Risk Statements ：: 23/24/25-50/53

Safety Statements ：: 23-27-45-60-61

RIDADR ：: UN 2647 6.1/PG 2

WGK Germany ：: 3

RTECS ：: OO3150000

F ：: 8

Autoignition Temperature：: 365 °C

TSCA ：: Yes

HazardClass ：: 6.1

PackingGroup ：: II

HS Code ：: 29269090

Toxicity：: LD50 i.p. in mice: 12.9 mg/kg (Jones, Israel)

Use：: The in vitro metabolsim of malononitrile has been described by Stern et al. In the presence of thiosulphate, brain, liver and kidney slices metabolized malononitrile to thiocyanate. The formation of thiocyanate from malononitrile and thiosulphate was greatest in the presence of liver slices, lowest in brain, and intermediate with kidney slices. The liver enzyme system was saturated at a concentration of 3.3 mM malononitrile and a pH optimum of 7.0. This enzyme system was inhibited by cysteine and glutathione and inactivated by boiling. Stern et al indicated that thiosulphate increased cyanide and thiocyanate formed from malononitrile in tissue slices.

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Baynoe Chem (Suzhou) Co., Ltd.