LUMIRACOXIB suppliers

LUMIRACOXIB

CAS:: 220991-20-8

MF:: C15H13ClFNO2

MW:: 293.72

Use：: As a second-generation, selective cyclooxygenase (COX-2) inhibitor, lumiracoxib is devoid of the gastrointestinal issues that plague other non-selective, nonsteroidal, anti-inflammatory drugs (NSAIDs) that crossover to COX-1. As an inhibitor of the inducible COX-2 that is up-regulated in pathological processes of pain and inflammation, lumiracoxib blocks the conversion of arachidonic acid to prostaglandins, the mediators of the pathological effects. It’s mode of binding to COX-2 has been found to differ from the other selective COX-2 inhibitors; the carboxylic acid forms hydrogen bonds with Tyr-385 and Ser-530 in the catalytic site rather than seeking interactions within the larger hydrophobic side pocket. Since lumiracoxib is mainly metabolized by CYP2C9, a study evaluating the co-administration of lumiracoxib with fluconazole, a potent inhibitor of CYP2C9, was conducted, and it concluded that there was no need for lumiracoxib dose adjustment, since changes in the systemic exposure were not significant. No serious adverse effects were reported, but in the small number of cases where treatment was discontinued, Gastro intestinal (GI) and musculoskeletal complaints were common.

More▼

You can find LUMIRACOXIB suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Hebei Chuanghai Biotechnology Co., Ltd

LUMIRACOXIB
Remarks: Purity: 99%|Package: 1KG;9.90;USD
CHINA Trader

￥9.90/1KG

Hebei Mujin Biotechnology Co.,Ltd

LUMIRACOXIB
Remarks: Purity: 99% | Package: 25KG
TEL: +86 13288715578
CHINA Service provider

￥0.00/25KG

Capot Chemical Co.,Ltd.

Lumiracoxib
Remarks: Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
TEL: 571-85586718
CHINA Trader

career henan chemical co

LUMIRACOXIB
Remarks: Purity: 99% | Package: 1kg;2USD
TEL: 0371-86658258
CHINA Reagent

￥2.00/1kg

CONIER CHEM AND PHARMA LIMITED

lumiracoxib
Remarks: Purity: 99% | Package: 1kg
CHINA Trader

SIMAGCHEM CORP

Lumiracoxib
Remarks: Purity: 0.99 | Package: 1kg,5kg,25kgs,200kgs;bulk
CHINA Trader

TargetMol Chemicals Inc.

Lumiracoxib
Remarks: Purity: 99.25% | Package: 50mg;70USD|10mg;31USD|25mg;48USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

Dideu Industries Group Limited

LUMIRACOXIB
Remarks: Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
TEL: +86-29-89586680
CHINA Trader

Dayang Chem (Hangzhou) Co.,Ltd.

Lumiracoxib
Remarks: Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot sales
TEL: 571-88938639
CHINA Trader

Zhejiang J&C Biological Technology Co.,Limited

LUMIRACOXIB
Remarks: Purity: 99% | Package: 5KG;1KG
TEL: 1-2135480471
CHINA Trader