HIRUDIN suppliers

HIRUDIN

CAS:: 8001-27-2

MF:: C287H440N80O113S7

MW:: 7043.4877

Use：: Refludan was launched in Germany for heparin-associated thrombocytopenia. Originally isolated from the saliva of leeches (Hirudo medicinalis), the gene for recombinant hirudin was synthesized and expressed in Saccharomyces cerevisiae. The isolated protein is 65 amino acids differing from the native protein by the first two amino acids (Leu1 and Thr2) and Tyr63 is not sulfated, while it does retain the three disulfide bonds. Refludan is a potent, specific and almost irreversible inhibitor of thrombin with which it forms a 1:1 complex. The N-terminal domain binds to the active catalytic site of thrombin, while the C-terminal end binds to the anion binding exosite (fibrinogen binding cleft). It has several advantages over heparin: it can inhibit thrombin bound to extracellular matrices, does not require antithrombin Ⅲ as a cofactor, is not inhibited by activated platelet nor increases platelet activity, and is a pure, single compound with a single mechanism of action. It is useful for myocardial infarcts, unstable angia and cardiovascular events. Heparin treatment can be inhibited by platelets activated by the Fc fragment of antibodies developed to the antigen of heparin-platelet factor 4. A corresponding inactivation of Refuldan is not known.

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You can find HIRUDIN suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Hebei Zhuanglai Chemical Trading Co Ltd

Hirudin
Remarks: Purity: 99% | Package: 1kg;150USD
CHINA Trader

￥150.00/1kg

Xi'an Kono chem co., Ltd.,

Hirudin
Remarks: Purity: 98% HPLC | Package: 25KG;1KG
TEL: 029-86107037
CHINA Trader

career henan chemical co

HIRUDIN
Remarks: Purity: 99% | Package: 1KG;7USD
TEL: 0371-86658258
CHINA Trader

￥7.00/1KG

Hubei Ipure Biology Co., Ltd

Hirudin
Remarks: Purity: 0.99 | Package: 5KG;1KG
CHINA Trader

Nanjing Duly Biotech Co.,Ltd

Hirudin recombinant
Remarks: Purity: BR,80ATU/MG | Package: 1mg；5mg；100u；250u
TEL: 02584699383
CHINA Trader

Hu Bei Jiutian Bio-medical Technology CO.,Ltd

Hirudin
Remarks: Purity: 0.99 | Package: 25kg,50kg,180kg,200kg,250kg,1000kg,as your needs | CustNote: as your needs
TEL: 027-88013699
CHINA Trader

Shaanxi LonierHerb Bio Technology Co Ltd

Hirudin
Remarks: Purity: 99% | Package: 5kg;1KG;0.5KG; 0.1KG;,0.01KG/BAG
TEL: +86-86-029-87551862
CHINA Trader

Watson Biotechnology Co.,Ltd

Hirudin recombinant
Remarks: Purity: 0.99 | Package: 1KG;25kg
CHINA Trader

Sigma-Aldrich Co. LLC.

Hirudin recombinant from yeast
Remarks: Brand: Sigma-Aldrich | Product Number: 94581 | Purity: lyophilized powder, white, >1500 U/vial
TEL: 800 558-9160
UNITED STATES Trader

￥974.00/1ea

Apollo Scientific Ltd.

Recombinant Hirudin
Remarks: Brand: Apollo Scientific | Product Number: BITP1576
TEL: 44 161 406 0505
UNITED KINGDOM Trader

￥80.00/2μg

￥196.00/10μg