Fluorescein isothiocyanate isomer I suppliers

Fluorescein isothiocyanate isomer I

CAS:: 3326-32-7

MF:: C21H11NO5S

MW:: 389.38

Properties

Melting point:：: >360 °C(lit.)

Boiling point:：: 708.6±60.0 °C(Predicted)

Density ：: 1.3423 (rough estimate)

refractive index ：: 1.5060 (estimate)

storage temp. ：: 2-8°C

solubility ：: Slightly soluble in DMSO, ethanol, methanol DMF and acetone

form ：: powder

pka：: 2.2, 4.4, 6.7(at 25℃)

color ：: White

PH Range：: Weak green uorescence (6.0) to strong green uorescence (7.2)

Water Solubility ：: practically insoluble

Sensitive ：: Moisture Sensitive

λmax：: 490nm

BRN ：: 1407295

Stability:：: Stability Stable, but moisture-sensitive. Incompatible with strong oxidizing agents, strong bases, amines, acids.

Major Application：: Magnetic nanowires, immunoassays, analyzing proteins, identifying chromosomes, Salmonella mosomes, diagnosis of cancer, kidney diseases, detecting pathogens, genes, Salmonella cells, toxoplasmosis, enzyme-mediated nucleic acid cleavage, surface molecules on colorectal cancers, treating cancer, chronic lymphocytic leukemia

Biological Applications：: Analyzing sugar chain; detecting iodide/iodate or total iodine; detecting/imaging thiols; detecting/quantifying biotin derivatives;16 diagnosing classical Hodgkin lymphoma (CHL) in lymph nodes; cellulose nanocrystals for bioimaging applications; treating neuroinflammation; treating/diagnosing cancer; PEO-PCL-PEO triblock copolymers for topical delivery; polymersomes in biomedical or cosmetic applications;apoptosis assay; as a substrate for measuring heparanase activity, human immunodeficiency virus (HIV-1) proteinase activity, kinase activity, phosphatase activity, β-lactamase activity, transglutaminase (TG2) activity; implantable drug-delivery devicess

InChIKey：: MHMNJMPURVTYEJ-UHFFFAOYSA-N

CAS DataBase Reference：: 3326-32-7(CAS DataBase Reference)

EPA Substance Registry System：: Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-5-isothiocyanato- (3326-32-7)

Use：: Fluorescein -5-isothiocyanate is a kind of fluorescent marker for biochemical applications. Reacts under mild conditions with primary amines and it is also used in modification of actin at lys-61, labelling of FAB and the modification of thiol groups.

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