Chlorzoxazone suppliers

Chlorzoxazone

CAS:: 95-25-0

MF:: C7H4ClNO2

MW:: 169.57

SecurityInformation

Symbol(GHS) ：: GHS07

Signal word ：: Warning

Hazard statements ：: H302-H315-H319-H335

Precautionary statements ：: P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

Hazard Codes ：: Xn,T,Xi

Risk Statements ：: 22-36/37/38-20/21/22

Safety Statements ：: 26-36-24/25-37/39

WGK Germany ：: 3

RTECS ：: DM5250000

Hazard Note ：: Toxic/Irritant

TSCA ：: Yes

HazardClass ：: IRRITANT

HS Code ：: 29349990

Toxicity：: LD50 in mice (mg/kg): 3650 orally, 380 i.p. (suspensions); 440 orally, 183 i.p. (solns of Na salt) (Hofrichter)

Use：: Chlorzoxazone is a benzoxazolone derivative that causes skeletal muscle relaxation and blocks spasticity in clinical studies. Chlorzoxazone enhances small and intermediate conductance calcium-activated potassium channels (EC50s = 87 and 98 μM for KCa2.2 and KCa3.1, respectively). The cytochrome P450 isoform CYP2E1 converts chlorzoxazone to 6-hydroxy chlorzoxazone . The urinary excretion of this 6-hydroxy metabolite is often used as a probe of CYP2E1 activity in studies of hepatotoxicity.

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You can find Chlorzoxazone suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Henan Tianfu Chemical Co.,Ltd.