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ChemicalBook >> CAS DataBase List >>Captopril

Captopril suppliers

Captopril

CAS:: 62571-86-2

MF:: C9H15NO3S

MW:: 217.29

SecurityInformation

Symbol(GHS) ：: GHS08

Signal word ：: Danger

Hazard statements ：: H341-H360F

Precautionary statements ：: P201-P308+P313

PPE：: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Codes ：: Xn,Xi

Risk Statements ：: 43-63-36/37/38-40

Safety Statements ：: 36/37-37/39-26-36-22

WGK Germany ：: 2

RTECS ：: UY0550000

HS Code ：: 29339900

Storage Class：: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications：: Muta. 2
Repr. 1B

Hazardous Substances Data：: 62571-86-2(Hazardous Substances Data)

Toxicity：: LD50 in mice (mg/kg): 1040 i.v.; 6000 orally (Keim)

Use：: Captopril, 1-[(2S)-3-mercapto-2-methyl-1-oxopropionyl]proline (Capoten), blocks the conversion of angiotensinI to angiotensin II by inhibiting the convertingenzyme. The rational development of captopril as an inhibitorof ACE was based on the hypothesis that ACE and carboxypeptidaseA functioned by similar mechanisms. It wasnoted that d-2-benzylsuccinic acid was a potent inhibitor ofcarboxypeptidase A, but not ACE. By use of this small molecule as a prototype, captopril was designed with a carboxylgroup on a proline and a thiol group was introduced toenhance the binding to the zinc ion of ACE. The importantbinding points at the active site of ACE are thought to be anarginine residue, which provides a cationic site that attracts acarboxylate ion, and a zinc ion, which can polarize a carbonylgroup of an amide function to make it more susceptible to hydrolysis.Hydrophobic pockets lie between these groups in theactive site, as does a functional group that forms a hydrogenbond with an amide carbonyl.

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You can find Captopril suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Shaanxi Dideu Medichem Co. Ltd

Captopril
Remarks: Purity: 99%|Package: 1KG;1.00;USD|25KG;2.00;USD|100KG;4.00;USD
TEL: +86-29-81139210
CHINA Trader

$1.00

$2.00

$4.00

Hebei Chuanghai Biotechnology Co,.LTD

Captopril
Remarks: Purity: 99%|Package: 1KG;5.00;USD|10KG;3.00;USD|50KG;2.00;USD
TEL: 86-+86-86-13131129325
CHINA Trader

$5.00

$3.00

$2.00

Henan Fengda Chemical Co., Ltd

Captopril
Remarks: Purity: 99% | Package: 1kg;35USD|1000kg;1.2USD
TEL: 0371-86557731
CHINA Trader

$35.00

$1.20

Henan Tianfu Chemical Co.,Ltd.

Captopril 25 mg Tablets
Remarks: Purity: 99% | Package: 25KG;5KG;1KG
TEL: 0371-+86-0371-55170693
CHINA Trader

Hefei TNJ Chemical Industry Co.,Ltd.

Captopril
Remarks: Purity: 99.9% | Package: 1KG;5USD
TEL: 0551-+86-0551-65418679
CHINA Reagent

career henan chemical co

Captopril
Remarks: Purity: 98% | Package: 1KG
TEL: 0371-86658258
CHINA Reagent

Xiamen AmoyChem Co., Ltd

Captopril
TEL: 86-+86-86-5926051114
CHINA Service provider

BOC Sciences

Captopril
Remarks: Purity: >98% | CustNote: Please reach out to us for more information about custom solutions.
TEL: +1-631-485-4226
UNITED STATES Trader

TargetMol Chemicals Inc.

Captopril
Remarks: Purity: 99.88% | Package: 100mg;48USD|200mg;59USD|50mg;40USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

$48.00

Hefei Hangang Pharmaceutical Technology Co., Ltd.

Captopril
Remarks: Purity: 0.99 | Package: 5KG;1KG
CHINA Trader