Canertinib dihydrochloride suppliers

Canertinib dihydrochloride

CAS:: 289499-45-2

MF:: C24H27Cl3FN5O3

MW:: 558.86

Use：: The HER family of receptor tyrosine kinases, EGFR, HER2, HER3, and HER4, mediate proliferation, migration, adhesion, differentiation, and survival in many different cell types and have been implicated in the development and progression of a variety of human tumors.Canertinib dihydrochloride is an irreversible quinazoline-based HER family tyrosine kinase inhibitor with IC50 values of 0.8, 19, and 7 nM for blocking in vitro activity of EGFR, HER2, and HER4, respectively. As a broadly applicable anti-cancer agent, it has been used to suppress proliferation of malignant peripheral nerve sheath tumor cells (effective concentration of 250-500 nM), to inhibit growth and induce dose-dependent apoptosis in a panel of neuroblastoma cell lines (IC50s = 0.94-2.45 μM), and to reduce proliferation of acute myeloid leukemia cells (IC50 = 0.27 μM). Canertinib dihydrochloride also displays anti-neoplastic activity towards T98G glioblastoma cells, HCT8 colorectal carcinoma cells, and cells expressing the breast cancer resistance protein.

More▼

You can find Canertinib dihydrochloride suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Hebei Yanxi Chemical Co., Ltd.

Canertinib dihydrochloride
Remarks: Purity: 0.99|Package: 1kg;0.00;USD
CHINA Manufacturer

￥0.00/1kg

ATK CHEMICAL COMPANY LIMITED

Canertinib dihydrochloride
Remarks: Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
TEL: 21-51877795
CHINA Reagent

career henan chemical co

Canertinib dihydrochloride
Remarks: Purity: 99% | Package: 1kg;8USD
TEL: 0371-86658258
CHINA Reagent

￥8.00/1kg

CONIER CHEM AND PHARMA LIMITED

canertinib dihydrochloride
Remarks: Purity: 0.99 | Package: 1kg
CHINA Trader

Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd

Canertinib dihydrochloride
Remarks: Purity: 0.99 | Package: Various Packaging; segregation
CHINA Service provider

TargetMol Chemicals Inc.

Canertinib dihydrochloride；CI-1033 dihydrochloride;Canertinib;PD-183805 dihydrochloride
Remarks: Purity: 99.23% | Package: 50mg;43USD|10mg;29USD|25mg;35USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

Hubei Ipure Biology Co., Ltd

Canertinib 2HC
Remarks: Purity: 0.99 | Package: 5KG;1KG
CHINA Trader

Dideu Industries Group Limited

Canertinib dihydrochloride
Remarks: Purity: 99.9%|Package: 1g;1.1USD
TEL: +86-29-89586680
CHINA Trader

￥1.10/1g

AFINE CHEMICALS LIMITED

CANERTINIB DIHYDROCHLORIDE
Remarks: Purity: 99% | Package: USP EP CP
TEL: 0571-85134551
CHINA Trader

Dayang Chem (Hangzhou) Co.,Ltd.

Canertinib dihydrochloride
Remarks: Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Top Quality
TEL: 571-88938639
CHINA Trader