BuforMin Hydrochloride suppliers

BuforMin Hydrochloride

CAS:: 1190-53-0

MF:: C6H16ClN5

MW:: 193.68

Use：: Buformin is a biguanide derivative with antihyperglycemic activity. It delays absorption of glucose from the gastrointestinal tract, increases insulin sensitivity and glucose utilization in peripheral cells, and inhibits hepatic gluconeogenesis. It can also deactivate the glycolytic pathway by suppressing glyceraldehyde 3-phosphate dehydrogenase gene expression, which can lead to lactic acidosis. Biguanides, such as buformin, are reported to inhibit the mitochondrial respiratory complex I by inhibiting ubiquinone reduction and by stimulating reactive oxygen species production via the complex I flavin. Some biguanides, including buformin, can also inhibit the mitochondrial ATP synthase. Buformin has also been examined for antitumor activity due to its ability to disrupt the unfolded protein response transcription program during glucose deprivation, which induces cell death in glucose-deprived tumor cells.BuforMin Hydrochloride is a biguanide derivative with antihyperglycemic activity. It delays absorption of glucose from the gastrointestinal tract, increases insulin sensitivity and glucose utilization in peripheral cells, and inhibits hepatic gluconeogenesis. BuforMin Hydrochloride has also been examined for antitumor activity due to its ability to disrupt the unfolded protein response transcription program during glucose deprivation, which induces cell death in glucose-deprived tumor cells.

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You can find BuforMin Hydrochloride suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

CONIER CHEM AND PHARMA LIMITED

buformin hydrochloride
Remarks: Purity: 99% | Package: 1kg
CHINA Trader

career henan chemical co

Buformin Hydrochloride
Remarks: Purity: ＞98% | Package: 1KG;9.8USD
TEL: 0371-86658258
CHINA Trader

￥9.80/1KG

TargetMol Chemicals Inc.

Buformin hydrochloride；NSC528218;NSC 528218;NSC-528218
Remarks: Purity: 97.83% | Package: 10mg;30USD|25mg;44USD|50mg;64USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

Shaanxi Dideu Medichem Co. Ltd

BuforMin Hydrochloride USP/EP/BP
Remarks: Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
TEL: +86-029-89586680
CHINA Trader