Bexarotene suppliers

Bexarotene

CAS:: 153559-49-0

MF:: C24H28O2

MW:: 348.48

Use：: Bexarotene was launched in the US for the treatment of manifestations of cutaneous T-cell lymphoma in patients who are refractory to at least one prior systemic therapy. The four step synthesis of bexarotene involves a double Friedel-Craft alkylation of toluene with 2,5-dichloro-2,5-dimethylhexane followed by acylation with monomethylterephthalic acid chloride, then Wittig methylidenation. Bexarotene is the first retinoid X receptor (RXR) agonist to be selective versus retinoid A receptors (RAR). Its activation of the three RXRα, β, γ isoforms induces cell differentiation and apoptosis and inhibits cell proliferation in several models of cancer. In phase ll/lll clinical trials, 48% of patients with refractory or persistent early-stage cutaneous T-cell lymphoma achieved a complete or partial response when treated with 300 mg/m2/day of bexarotene. It was shown in phase I trials that this second-generation retinoid was substantially less toxic than the broad-spectrum or RARselective retinoids.

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You can find Bexarotene suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Finetech Industry Limited

Bexarotene
Remarks: Purity: 98% | Package: 1g,10g,25g,100g,500g,1kg
TEL: 27-+86-27-8746-5837
CHINA Trader

Henan Tianfu Chemical Co.,Ltd.

Bexarotene 153559-49-0
Remarks: Purity: 99% | Package: 25KG;5KG;1KG
TEL: 0371-+86-0371-55170693
CHINA Trader

career henan chemical co

Bexarotene
Remarks: Purity: 99% | Package: 1kg;2USD
TEL: 0371-86658258
CHINA Reagent

$2.00

Zhejiang ZETian Fine Chemicals Co. LTD

Bexarotene
Remarks: Purity: 0.99 | Package: 5KG;1KG
CHINA Trader

BOC Sciences

Bexarotene
Remarks: Purity: >98% | CustNote: Please reach out to us for more information about custom solutions.
TEL: +1-631-485-4226
UNITED STATES Trader

Shaanxi Dideu Medichem Co. Ltd

Bexarotene
Remarks: Purity: 99% | Package: 5mg;USD|100mg;USD|10g;USD|500g;USD|25KG;USD
TEL: 029-+86-29-87569262
CHINA Trader

RongNa Biotechnology Co.,Ltd

Bexarotene
Remarks: Purity: 0.99
TEL: 86-+86-86-13583358881
CHINA Trader

Chemsigma International Co., Ltd.

Bexarotene
Remarks: Purity: 98% | Package: 1ASSAYS;USD
TEL: +86-2558742998
CHINA Trader

AFINE CHEMICALS LIMITED

BEXAROTENE
Remarks: Purity: 99% | Package: USP EP CP
TEL: 571-85134551
CHINA Trader

Baoji Guokang Healthchem Co., Ltd.

Bexarotene
Remarks: Purity: 0.98 | Package: 25KG;1KG
TEL: +86-0917-3909592
CHINA Trader