ATB-337 suppliers

ATB-337

CAS:: 912758-00-0

MF:: C23H15Cl2NO2S3

MW:: 504.47

Use：: Hydrogen sulfide (H2S) is a naturally occurring gasotransmitter with vasodilator and inflammatory modulating activity. Non-steroidal anti-inflammatory drugs (NSAIDs), such as indomethacin, diclofenac, and ibuprofen, are some of the most commonly used anti-inflammatory drugs available but exhibit significant side effects, particularly gastric damage, when used chronically. ATB-337 is a hybrid molecule of an H2S donor and the NSAID diclofenac. In rats, diclofenac at 10-50 μmol/kg caused significant gastrointestinal damage, whereas no damage was observed with ATB-337 treatment at the same dose. ATB-337 at 50 μmol/kg does not promote leukocyte adherence to vascular endothelium, an effect observed with diclofenac treatment alone. COX-1 and COX-2 were inhibited with similar efficacy by diclofenac and ABT-337. An increase in expression of the pro-inflammatory mediator TNF-α, as well as, the adhesion molecules ICAM-1 and LFA-1 were not observed in rats treated with 50 μmol/kg ABT-337, effects seen with equimolar doses of diclofenac. These results indicate that H2S-releasing derivatives of NSAIDs may prove to be more effective anti-inflammatory agents than traditional NSAIDs alone.[Cayman Chemical]

More▼

You can find ATB-337 suppliers, manufacturers, and distributors from countries such as China, United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

TargetMol Chemicals Inc.

ATB-337
Remarks: Package: 1mg;88USD|5mg;388USD|10mg;685USD
TEL: +1-781-999-5354
UNITED STATES Trader

Cayman Chemical Company

ATB-337
Remarks: Brand: Caymanchem | Product Number: 10277 | Purity: ≥98%
TEL: (800) 364-9897
UNITED STATES Trader

￥28.00/1 mg

￥126.00/5 mg

￥224.00/10 mg

￥980.00/50 mg

DC Chemicals

ATB-337
Remarks: Brand：dcchemicals | Product Number：DC36098
TEL: +86-21-58447131
UNITED STATES Trader

1Pluschem LLC

Remarks: Brand:1pchem | Product Number:1P00GTR4 | Purity:≥98%
TEL: (858)215-1656
UNITED STATES Trader

￥94.00/1mg

￥1666.00/50mg

AK Scientific, Inc.

4-(3-Thioxo-3H-1,2-dithiol-5-yl)phenylester-2-((2,6-dichlorophenyl)amino)-benzeneaceticacid
Remarks: Brand：aksci | Product Number：1396AH
TEL: 650 494 8666
UNITED STATES Trader

￥270.00/5mg

Beijing Dongge Boye Biotechnology Co., Ltd.

ATB-337
TEL: 4008558271
CHINA Trader

Shanghai Haoran Biotechnology Co., Ltd.

ATB-337
TEL: 021-54046791
CHINA Trader

TargetMol Chemicals Inc.

ATB-337
Remarks: Purity: 0 | Package: 1mg
CHINA Trader

MedBioPharmaceutical Technology Inc

ATB-337
Remarks: Purity: 98% | Package: 10mg; 50mg; 5mg | CustNote: Medbio
TEL: 021-69568360
CHINA Reagent

Neobioscience Co., Ltd.

ATB-337
TEL: 4006-800-892
CHINA Trader