AST 487 suppliers

AST 487

CAS:: 630124-46-8

MF:: C26H30F3N7O2

MW:: 529.56

Use：: AST-487 is an inhibitor of RET (IC50 = 0.88 μM), FLT3 (Ki = 0.52 μM), KDR (IC50 = 0.17 μM), c-Abl (IC50 = 0.02 μM), and c-Kit (IC50 = 0.5 μM). It has been shown to inhibit RET autophosphorylation and activation of downstream effectors and to prevent the growth of human thyroid cancer cell lines with activating mutations of RET but not of lines without RET mutations. In xenografts of NIH3T3 cells expressing oncogenic RET and of the MTC cell line TT in nude mice, AST-487 dose dependently inhibited tumor growth. It also demonstrates antiproliferative effects on primary cells from acute myelocytic leukemia patients and on cell lines expressing FLT3-ITD or FLT3 kinase domain point mutants.[Cayman Chemical]

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You can find AST 487 suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

ATK CHEMICAL COMPANY LIMITED

AST 487
Remarks: Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
TEL: 21-51877795
CHINA Reagent

career henan chemical co

AST 487
Remarks: Purity: 95-99% | Package: 1KG;1USD
TEL: 0371-+86-0371-86658258
CHINA Trader

￥1.00/1KG

Zhejiang J&C Biological Technology Co.,Limited

AST 487
Remarks: Purity: 99% | Package: 5KG;1KG | CustNote: AST 487
TEL: 1-2135480471
CHINA Trader

Aladdin Scientific

AST-487 (NVP-AST487)
Remarks: Purity: 98% | Package: $42.9/2mg;$88.9/5mg;$147.9/10mg;$246.9/25mg;$444.9/50mg;$840.9/100mg;Bulk packag | CustNote: 98%
TEL: +1(833)-552-7181
UNITED STATES Trader

Amadis Chemical Company Limited

Urea,N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]-
Remarks: Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A899841
TEL: 571-571-89925085
CHINA Reagent