Anagrelide hydrochloride suppliers

Anagrelide hydrochloride

CAS:: 58579-51-4

MF:: C10H8Cl3N3O

MW:: 292.55

Use：: Anagrelide hydrochloride was launched in the US for thrombocytosis (essential or associated with chronic myelogenous leukemia). The imidazoquinazoline derivative can be prepared from 2,5,6-trichloro-3,4-dihydropyrimidine via alkylation with ethyl bromoacetate followed by heating with ethanolic ammonia or treatment of N-(a-amino- 5,6-dichlorobenzyl)glycine ethyl ester with cyanogen bromide. As a result of its anti-cAMP phosphodiesterase (PDE Ⅲ) activity, Anagrelide hydrochloride was initially tested as a platelet aggregation inhibitor. However it was found that at much lower concentrations it became thrombocytopenic. While the mechanism is not fully understood, it did not shorten platelet survival nor inhibit the formation of colony-forming unitsmegakaryocytes (CFU-M) but primarily interfered with the maturation of megakaryocytes (reduction in size with altered ploidy). It did decrease peripheral vascular resistance and had a positive inotropic effect.

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You can find Anagrelide hydrochloride suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

career henan chemical co

Anagrelide hydrochloride
Remarks: Purity: 99% | Package: 1kg;2USD
TEL: 0371-86658258
CHINA Reagent

￥2.00/1kg

Chongqing Chemdad Co., Ltd

Anagrelide hydrochloride
Remarks: Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
TEL: 023-+86-023-61398051
CHINA Trader

CONIER CHEM AND PHARMA LIMITED

anagrelide hydrochloride
Remarks: Purity: 0.99 | Package: 25g
CHINA Trader

Shaanxi Dideu Medichem Co. Ltd

Anagrelide hydrochloride
Remarks: Purity: 99% HPLC | Package: 5mg;USD|1g;USD|500g;USD|25KG;USD|200KG;USD
TEL: +86-29-87569265
CHINA Trader

SIMAGCHEM CORP

Anagrelide Hcl
Remarks: Purity: 0.99 | Package: 1kg,5kg,25kgs,200kgs;bulk
CHINA Trader

Hefei TNJ Chemical Industry Co.,Ltd.

Anagrelide Hydrochloride
TEL: 0551-0551-65418671
CHINA Reagent

Dideu Industries Group Limited

Anagrelide hydrochloride
Remarks: Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
TEL: 029-+86-29-89586680
CHINA Trader

AFINE CHEMICALS LIMITED

ANAGRELIDE HYDROCHLORIDE
Remarks: Purity: 99% | Package: USP EP CP
TEL: 0571-0571-85134551
CHINA Trader

CD Chemical Group Limited

Anagrelide hydrochloride
Remarks: Purity: 0.99 | Package: 1000KG;100KG;5KG;1KG
CHINA Trader

Alfa Chemistry

Anagrelide Hydrochloride
TEL: +1-5166625404
UNITED STATES Reagent